Detection of prospective memory deficits in mild cognitive impairment of suspected Alzheimer's disease etiology using a novel event-based prospective memory task.
AffiliationSchool of Psychology, University College Dublin, Dublin, Ireland. Alberto.Blanco-Campal@hse.ie
Aged, 80 and over
MetadataShow full item record
CitationDetection of prospective memory deficits in mild cognitive impairment of suspected Alzheimer's disease etiology using a novel event-based prospective memory task. 2009, 15 (1):154-9 J Int Neuropsychol Soc
JournalJournal of the International Neuropsychological Society : JINS
AbstractWe investigated the relative discriminatory efficacy of an event-based prospective memory (PM) task, in which specificity of the instructions and perceptual salience of the PM cue were manipulated, compared with two widely used retrospective memory (RM) tests (Rivermead Paragraph Recall Test and CERAD-Word List Test), when detecting mild cognitive impairment of suspected Alzheimer's disease etiology (MCI-AD) (N = 19) from normal controls (NC) (N = 21). Statistical analyses showed high discriminatory capacity of the PM task for detecting MCI-AD. The Non-Specific-Non-Salient condition proved particularly useful in detecting MCI-AD, possibly reflecting the difficulty of the task, requiring more strategic attentional resources to monitor for the PM cue. With a cutoff score of <4/10, the Non-Specific-Non-Salient condition achieved a sensitivity = 84%, and a specificity = 95%, superior to the most discriminative RM test used (CERAD-Total Learning: sensitivity = 83%; specificity = 76%). Results suggest that PM is an early sign of memory failure in MCI-AD and may be a more pronounced deficit than retrospective failure, probably reflecting the greater self-initiated retrieval demands involved in the PM task used. Limitations include the relatively small sample size, and the use of a convenience sample (i.e. memory clinic attenders and healthy active volunteers), reducing the generalizability of the results, which should be regarded as preliminary. (JINS, 2009, 15, 154-159.).
- [A detection of very mild Alzheimer's disease and MCI by memory complaints and deterioration of IADL in a questionnaire for a memory clinic].
- Authors: Ueda M, Takayama Y, Koyama Y, Osada H
- Issue date: 2006 Oct
- False recognition helps to distinguish patients with Alzheimer's disease and amnestic MCI from patients with other kinds of dementia.
- Authors: Hildebrandt H, Haldenwanger A, Eling P
- Issue date: 2009
- [Prospective memory in normal aging and Alzheimer's disease].
- Authors: Eusop-Roussel E, Ergis AM
- Issue date: 2008 Dec
- [Memory deficit in patients with subcortical vascular cognitive impairment versus Alzheimer-type dementia: the sensitivity of the 'word list' subtest on the Wechsler Memory Scale-III].
- Authors: Suades-González E, Jódar-Vicente M, Pérdrix-Solàs D
- Issue date: 2009 Dec 16-31
- Working memory and control of attention in persons with Alzheimer's disease and mild cognitive impairment.
- Authors: Belleville S, Chertkow H, Gauthier S
- Issue date: 2007 Jul