Profound and persistent painful paclitaxel peripheral neuropathy in a premenopausal patient.
Affiliation
Department of Medical Oncology, Mid-Western Cancer Centre, Mid-Western Regional Hospital, Limerick, Ireland. keithi.quintyne@hse.ieIssue Date
2011MeSH
AdultAntineoplastic Agents, Phytogenic
Brain
Breast Neoplasms
Female
Humans
Magnetic Resonance Imaging
Neuroimaging
Paclitaxel
Peripheral Nervous System Diseases
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Profound and persistent painful paclitaxel peripheral neuropathy in a premenopausal patient. 2011, 2011: BMJ Case RepPublisher
BMJ case reportsJournal
BMJ case reportsDOI
10.1136/bcr.12.2010.3645PubMed ID
22696717Abstract
The authors herein report the case of a 35-year-old woman undergoing adjuvant therapy for node positive breast cancer, who presented with short and rapidly progressive history of bilateral lower limb symptoms of peripheral neuropathy following therapy with paclitaxel. MRI of her neural axis revealed no leptomeningeal enhancement or focal metastatic lesions. Neurophysiological tests favoured toxic sensory axonal polyneuropathy. She remains symptomatic following discontinuation of therapy 20 months ago, and is under review with pain management.Item Type
ArticleLanguage
enISSN
1757-790Xae974a485f413a2113503eed53cd6c53
10.1136/bcr.12.2010.3645
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