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dc.contributor.authorMadigan, Kevin
dc.contributor.authorBrennan, Daria
dc.contributor.authorLawlor, Elizabeth
dc.contributor.authorTurner, Niall
dc.contributor.authorKinsella, Anthony
dc.contributor.authorO'Connor, John J
dc.contributor.authorRussell, Vincent
dc.contributor.authorWaddington, John L
dc.contributor.authorO'Callaghan, Eadbhard
dc.date.accessioned2013-08-15T13:44:58Z
dc.date.available2013-08-15T13:44:58Z
dc.date.issued2013-01
dc.identifier.citationA multi-center, randomized controlled trial of a group psychological intervention for psychosis with comorbid cannabis dependence over the early course of illness. 2013, 143 (1):138-42 Schizophr. Res.en_GB
dc.identifier.issn1573-2509
dc.identifier.pmid23187069
dc.identifier.doi10.1016/j.schres.2012.10.018
dc.identifier.urihttp://hdl.handle.net/10147/298891
dc.descriptionBACKGROUND: Patients who experience the onset of psychotic illness with a comorbid diagnosis of cannabis dependence experience poor clinical outcomes. Few studies have identified interventions that reduce cannabis use and improve clinical outcome in this population. AIMS: We undertook a multi-center, randomized controlled trial of a group psychological intervention for psychosis with comorbid cannabis dependence to determine whether there was any impact on cannabis use symptoms, global functioning, insight, attitudes to treatment and subjective quality of life. METHOD: Across three centers, we compared a group psychological intervention, based on cognitive behavioral therapy and motivational interviewing, with treatment as usual among patients experiencing their first psychotic episode or early in the course of psychotic illness. Substance misuse and indices of clinical outcome were assessed at baseline, 3months and 1year. RESULTS: At 3month and 1year follow-ups, there was no evidence for an intervention effect on cannabis use, symptoms, global functioning insight or attitude to treatment. However, the intervention improved subjective quality of life at 3months and this effect was sustained at 1year. CONCLUSIONS: Over the early phase of psychotic illness, group psychological interventions for those with comorbid cannabis dependence improved subjective quality of life. However, this was not associated with reduction in use of cannabis or improvement in clinical outcomes.en_GB
dc.description.abstractPatients who experience the onset of psychotic illness with a comorbid diagnosis of cannabis dependence experience poor clinical outcomes. Few studies have identified interventions that reduce cannabis use and improve clinical outcome in this population.
dc.description.abstractWe undertook a multi-center, randomized controlled trial of a group psychological intervention for psychosis with comorbid cannabis dependence to determine whether there was any impact on cannabis use symptoms, global functioning, insight, attitudes to treatment and subjective quality of life.
dc.description.abstractAcross three centers, we compared a group psychological intervention, based on cognitive behavioral therapy and motivational interviewing, with treatment as usual among patients experiencing their first psychotic episode or early in the course of psychotic illness. Substance misuse and indices of clinical outcome were assessed at baseline, 3months and 1year.
dc.description.abstractAt 3month and 1year follow-ups, there was no evidence for an intervention effect on cannabis use, symptoms, global functioning insight or attitude to treatment. However, the intervention improved subjective quality of life at 3months and this effect was sustained at 1year.
dc.description.abstractOver the early phase of psychotic illness, group psychological interventions for those with comorbid cannabis dependence improved subjective quality of life. However, this was not associated with reduction in use of cannabis or improvement in clinical outcomes.
dc.language.isoenen
dc.rightsArchived with thanks to Schizophrenia researchen_GB
dc.subjectPSYCHOTIC DISORDERen_GB
dc.subjectCANNABISen_GB
dc.subject.meshAdult
dc.subject.meshAge Factors
dc.subject.meshAnalysis of Variance
dc.subject.meshAttitude
dc.subject.meshCognitive Therapy
dc.subject.meshFemale
dc.subject.meshFollow-Up Studies
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMarijuana Abuse
dc.subject.meshPsychiatric Status Rating Scales
dc.subject.meshPsychotic Disorders
dc.subject.meshQuality of Life
dc.subject.meshRecurrence
dc.subject.meshSeverity of Illness Index
dc.subject.meshYoung Adult
dc.titleA multi-center, randomized controlled trial of a group psychological intervention for psychosis with comorbid cannabis dependence over the early course of illness.en_GB
dc.typeArticleen
dc.contributor.departmentSt. John of God Adult Mental Health Services, Cluain Mhuire Family Centre, Blackrock, Co. Dublin, Ireland; DETECT Early Intervention in Psychosis Service, Blackrock, Co. Dublin, Ireland. kevin.madigan@sjog.ieen_GB
dc.identifier.journalSchizophrenia researchen_GB
html.description.abstractPatients who experience the onset of psychotic illness with a comorbid diagnosis of cannabis dependence experience poor clinical outcomes. Few studies have identified interventions that reduce cannabis use and improve clinical outcome in this population.
html.description.abstractWe undertook a multi-center, randomized controlled trial of a group psychological intervention for psychosis with comorbid cannabis dependence to determine whether there was any impact on cannabis use symptoms, global functioning, insight, attitudes to treatment and subjective quality of life.
html.description.abstractAcross three centers, we compared a group psychological intervention, based on cognitive behavioral therapy and motivational interviewing, with treatment as usual among patients experiencing their first psychotic episode or early in the course of psychotic illness. Substance misuse and indices of clinical outcome were assessed at baseline, 3months and 1year.
html.description.abstractAt 3month and 1year follow-ups, there was no evidence for an intervention effect on cannabis use, symptoms, global functioning insight or attitude to treatment. However, the intervention improved subjective quality of life at 3months and this effect was sustained at 1year.
html.description.abstractOver the early phase of psychotic illness, group psychological interventions for those with comorbid cannabis dependence improved subjective quality of life. However, this was not associated with reduction in use of cannabis or improvement in clinical outcomes.


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