Leucocyte esterase in the rapid diagnosis of paediatric septic arthritis.
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Affiliation
Dept. of Trauma and Orthopaedic Surgery, Children's University Hospital, Temple St., Dublin, Ireland. endagkelly@gmail.comIssue Date
2013-02MeSH
Arthritis, InfectiousCarboxylic Ester Hydrolases
Child
Humans
Models, Biological
Synovial Fluid
Time Factors
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Leucocyte esterase in the rapid diagnosis of paediatric septic arthritis. 2013, 80 (2):191-3 Med. HypothesesJournal
Medical hypothesesDOI
10.1016/j.mehy.2012.11.026PubMed ID
23257651Abstract
Septic arthritis may affect any age group but is more common in the paediatric population. Infection is generally bacterial in nature. Prompt diagnosis is crucial, as delayed treatment is associated with lifelong joint dysfunction. A clinical history and application of Kocher's criteria may indicate that there is a septic arthritis. However, definitive diagnosis is made on culture of septic synovial fluid. The culture process can take over 24h for the initial culture to yield bacterial colonies. Leucocyte esterase is released by leucocytes at the site of an infection. We hypothesise that leucocyte esterase can be utilized in the rapid diagnosis of septic arthritis and shorten the time to decisive treatment whilst simultaneously decreasing unnecessary treatment of non-septic joints.Item Type
ArticleLanguage
enISSN
1532-2777ae974a485f413a2113503eed53cd6c53
10.1016/j.mehy.2012.11.026
Scopus Count
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