AffiliationDepartment of Medical Oncology, Our Lady of Lourdes Hospital, Drogheda, Ireland. email@example.com
Predictive Value of Tests
Tumor Markers, Biological
MetadataShow full item record
CitationProteomic classification of breast cancer. 2012, 13 (12):1495-509 Curr Drug Targets
JournalCurrent drug targets
AbstractBeing a significant health problem that affects patients in various age groups, breast cancer has been extensively studied to date. Recently, molecular breast cancer classification has advanced significantly with the availability of genomic profiling technologies. Proteomic technologies have also advanced from traditional protein assays including enzyme-linked immunosorbent assay, immunoblotting and immunohistochemistry to more comprehensive approaches including mass spectrometry and reverse phase protein lysate arrays (RPPA). The purpose of this manuscript is to review the current protein markers that influence breast cancer prediction and prognosis and to focus on novel advances in proteomic classification of breast cancer.
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