Effect of injury on S1 dorsal root ganglia in an experimental model of neuropathic faecal incontinence.

Authors
Peirce, C
O'Herlihy, C
O'Connell, P R
Jones, J F X
Affiliation
School of Medicine and Medical Science, University College Dublin, Belfield, Dublin, Ireland.
Issue Date
2011-08
MeSH
Activating Transcription Factor 3
Animals
Biological Markers
Catheterization
Fecal Incontinence
Female
Ganglia, Spinal
Nerve Crush
Rats
Rats, Wistar

Metadata
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Citation
Effect of injury on S1 dorsal root ganglia in an experimental model of neuropathic faecal incontinence. 2011, 98 (8):1155-9 Br J Surg
Publisher
The British journal of surgery
Journal
The British journal of surgery
URI
http://hdl.handle.net/10147/296279
DOI
10.1002/bjs.7431
PubMed ID
21618494
Abstract
An experimental model of neuropathic faecal incontinence has recently been established. This study aimed to quantify and compare the effect of crush and compression injury on first-order sensory neurones of the inferior rectal nerve (IRN) using a nuclear marker of axonal injury, activating transcription factor (ATF) 3.
Item Type
Article
Language
en
ISSN
1365-2168
Sponsors
RCSI and UCD researach grant incorporating the Gussie Mehigan Sc
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