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dc.contributor.authorOlivieri, Aldo
dc.contributor.authorTipton, Keith F
dc.contributor.authorO'Sullivan, Jeff
dc.date.accessioned2013-05-14T11:43:46Z
dc.date.available2013-05-14T11:43:46Z
dc.date.issued2012-04
dc.identifier.citationCharacterization of the in vitro binding and inhibition kinetics of primary amine oxidase/vascular adhesion protein-1 by glucosamine. 2012, 1820 (4):482-7 Biochim. Biophys. Actaen_GB
dc.identifier.issn0006-3002
dc.identifier.pmid22202180
dc.identifier.doi10.1016/j.bbagen.2011.12.009
dc.identifier.urihttp://hdl.handle.net/10147/291083
dc.description.abstractPrimary-amine oxidase (PrAO) catalyzes the oxidative deamination of endogenous and exogenous primary amines and also functions, in some tissues, as an inflammation-inducible endothelial factor, known as vascular adhesion protein-1. VAP-1 mediates the slow rolling and adhesion of lymphocytes to endothelial cells in a number of inflammatory conditions, including inflammation of the synovium.
dc.language.isoenen
dc.rightsArchived with thanks to Biochimica et biophysica actaen_GB
dc.subject.meshAmine Oxidase (Copper-Containing)
dc.subject.meshAnimals
dc.subject.meshCattle
dc.subject.meshCell Adhesion
dc.subject.meshDeamination
dc.subject.meshEndothelial Cells
dc.subject.meshGlucosamine
dc.subject.meshHydrogen Peroxide
dc.subject.meshLeukocyte Rolling
dc.subject.meshLymphocytes
dc.subject.meshOsteoarthritis
dc.subject.meshOxidation-Reduction
dc.titleCharacterization of the in vitro binding and inhibition kinetics of primary amine oxidase/vascular adhesion protein-1 by glucosamine.en_GB
dc.typeArticleen
dc.contributor.departmentSchool of Biochemistry and Immunology, Trinity College Dublin, Ireland. oliviera@tcd.ieen_GB
dc.identifier.journalBiochimica et biophysica actaen_GB
dc.description.provinceLeinsteren
html.description.abstractPrimary-amine oxidase (PrAO) catalyzes the oxidative deamination of endogenous and exogenous primary amines and also functions, in some tissues, as an inflammation-inducible endothelial factor, known as vascular adhesion protein-1. VAP-1 mediates the slow rolling and adhesion of lymphocytes to endothelial cells in a number of inflammatory conditions, including inflammation of the synovium.


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