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    The case for intraocular delivery of PPAR agonists in the treatment of diabetic retinopathy.

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    Authors
    Treacy, Maxwell P
    Hurst, Tara P
    Affiliation
    Royal Victoria Eye and Ear Hospital, Adelaide Road, Dublin 2, Dublin, Ireland. max@treacy.ie
    Issue Date
    2012-09
    MeSH
    Diabetic Retinopathy
    Eye
    Fenofibrate
    Humans
    Hypolipidemic Agents
    Injections
    PPAR alpha
    Treatment Outcome
    
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    Citation
    The case for intraocular delivery of PPAR agonists in the treatment of diabetic retinopathy. 2012, 12:46 BMC Ophthalmol
    Journal
    BMC ophthalmology
    URI
    http://hdl.handle.net/10147/283772
    DOI
    10.1186/1471-2415-12-46
    PubMed ID
    22937835
    Additional Links
    http://www.biomedcentral.com/content/pdf/1471-2415-12-46.pdf
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532122/pdf/1471-2415-12-46.pdf
    Abstract
    Systemic therapeutics targeting the peroxisome proliferator-activated receptors have been found to be beneficial in the treatment of diabetic retinopathy. In this paper, we provide a rationale for the use of these therapeutics as intraocular agents. In addition, we introduce the peroxisome proliferator-activated receptors and describe their functions in response to the drugs.
    Item Type
    Article
    Language
    en
    ISSN
    1471-2415
    ae974a485f413a2113503eed53cd6c53
    10.1186/1471-2415-12-46
    Scopus Count
    Collections
    Royal Victoria Eye and Ear Hospital

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