The case for intraocular delivery of PPAR agonists in the treatment of diabetic retinopathy.
Affiliation
Royal Victoria Eye and Ear Hospital, Adelaide Road, Dublin 2, Dublin, Ireland. max@treacy.ieIssue Date
2012-09MeSH
Diabetic RetinopathyEye
Fenofibrate
Humans
Hypolipidemic Agents
Injections
PPAR alpha
Treatment Outcome
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The case for intraocular delivery of PPAR agonists in the treatment of diabetic retinopathy. 2012, 12:46 BMC OphthalmolJournal
BMC ophthalmologyDOI
10.1186/1471-2415-12-46PubMed ID
22937835Additional Links
http://www.biomedcentral.com/content/pdf/1471-2415-12-46.pdfhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3532122/pdf/1471-2415-12-46.pdf
Abstract
Systemic therapeutics targeting the peroxisome proliferator-activated receptors have been found to be beneficial in the treatment of diabetic retinopathy. In this paper, we provide a rationale for the use of these therapeutics as intraocular agents. In addition, we introduce the peroxisome proliferator-activated receptors and describe their functions in response to the drugs.Item Type
ArticleLanguage
enISSN
1471-2415ae974a485f413a2113503eed53cd6c53
10.1186/1471-2415-12-46
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