Chemotherapy for resistant or recurrent gestational trophoblastic neoplasia.
dc.contributor.author | Alazzam, Mo'iad | |
dc.contributor.author | Tidy, John | |
dc.contributor.author | Osborne, Raymond | |
dc.contributor.author | Coleman, Robert | |
dc.contributor.author | Hancock, Barry W | |
dc.contributor.author | Lawrie, Theresa A | |
dc.date.accessioned | 2013-02-25T14:24:01Z | |
dc.date.available | 2013-02-25T14:24:01Z | |
dc.date.issued | 2012-12 | |
dc.identifier.citation | Chemotherapy for resistant or recurrent gestational trophoblastic neoplasia. 2012, 12:CD008891 Cochrane Database Syst Rev | en_GB |
dc.identifier.issn | 1469-493X | |
dc.identifier.pmid | 23235667 | |
dc.identifier.doi | 10.1002/14651858.CD008891.pub2 | |
dc.identifier.uri | http://hdl.handle.net/10147/270372 | |
dc.description.abstract | Gestational trophoblastic neoplasia (GTN) is a highly curable group of pregnancy-related tumours; however, approximately 25% of GTN tumours will be resistant to, or will relapse after, initial chemotherapy. These resistant and relapsed lesions will require salvage chemotherapy with or without surgery. Various salvage regimens are used worldwide. It is unclear which regimens are the most effective and the least toxic. | |
dc.language.iso | en | en |
dc.relation.url | http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008891.pub2/pdf | en_GB |
dc.rights | Archived with thanks to Cochrane database of systematic reviews (Online) | en_GB |
dc.subject.mesh | Drug Resistance, Neoplasm | |
dc.subject.mesh | Female | |
dc.subject.mesh | Gestational Trophoblastic Disease | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Neoplasm Recurrence, Local | |
dc.subject.mesh | Pregnancy | |
dc.title | Chemotherapy for resistant or recurrent gestational trophoblastic neoplasia. | en_GB |
dc.type | Systematic Review | en |
dc.contributor.department | Department of Gynaecology, The Galway Clinic, Doughiska, Galway, Ireland. moiad@doctors.org.uk | en_GB |
dc.identifier.journal | Cochrane database of systematic reviews (Online) | en_GB |
dc.description.province | Connacht | en |
html.description.abstract | Gestational trophoblastic neoplasia (GTN) is a highly curable group of pregnancy-related tumours; however, approximately 25% of GTN tumours will be resistant to, or will relapse after, initial chemotherapy. These resistant and relapsed lesions will require salvage chemotherapy with or without surgery. Various salvage regimens are used worldwide. It is unclear which regimens are the most effective and the least toxic. |