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    Chemotherapy for resistant or recurrent gestational trophoblastic neoplasia.

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    Authors
    Alazzam, Mo'iad
    Tidy, John
    Osborne, Raymond
    Coleman, Robert
    Hancock, Barry W
    Lawrie, Theresa A
    Affiliation
    Department of Gynaecology, The Galway Clinic, Doughiska, Galway, Ireland. moiad@doctors.org.uk
    Issue Date
    2012-12
    MeSH
    Drug Resistance, Neoplasm
    Female
    Gestational Trophoblastic Disease
    Humans
    Neoplasm Recurrence, Local
    Pregnancy
    
    Metadata
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    Citation
    Chemotherapy for resistant or recurrent gestational trophoblastic neoplasia. 2012, 12:CD008891 Cochrane Database Syst Rev
    Journal
    Cochrane database of systematic reviews (Online)
    URI
    http://hdl.handle.net/10147/270372
    DOI
    10.1002/14651858.CD008891.pub2
    PubMed ID
    23235667
    Additional Links
    http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD008891.pub2/pdf
    Abstract
    Gestational trophoblastic neoplasia (GTN) is a highly curable group of pregnancy-related tumours; however, approximately 25% of GTN tumours will be resistant to, or will relapse after, initial chemotherapy. These resistant and relapsed lesions will require salvage chemotherapy with or without surgery. Various salvage regimens are used worldwide. It is unclear which regimens are the most effective and the least toxic.
    Item Type
    Systematic Review
    Language
    en
    ISSN
    1469-493X
    ae974a485f413a2113503eed53cd6c53
    10.1002/14651858.CD008891.pub2
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    Galway Clinic

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