Chemotherapy for resistant or recurrent gestational trophoblastic neoplasia.
Affiliation
Department of Gynaecology, The Galway Clinic, Doughiska, Galway, Ireland. moiad@doctors.org.ukIssue Date
2012-12MeSH
Drug Resistance, NeoplasmFemale
Gestational Trophoblastic Disease
Humans
Neoplasm Recurrence, Local
Pregnancy
Metadata
Show full item recordCitation
Chemotherapy for resistant or recurrent gestational trophoblastic neoplasia. 2012, 12:CD008891 Cochrane Database Syst RevJournal
Cochrane database of systematic reviews (Online)DOI
10.1002/14651858.CD008891.pub2PubMed ID
23235667Abstract
Gestational trophoblastic neoplasia (GTN) is a highly curable group of pregnancy-related tumours; however, approximately 25% of GTN tumours will be resistant to, or will relapse after, initial chemotherapy. These resistant and relapsed lesions will require salvage chemotherapy with or without surgery. Various salvage regimens are used worldwide. It is unclear which regimens are the most effective and the least toxic.Item Type
Systematic ReviewLanguage
enISSN
1469-493Xae974a485f413a2113503eed53cd6c53
10.1002/14651858.CD008891.pub2