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    Prevalence of item level negative symptoms in first episode psychosis diagnoses.

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    Authors
    Lyne, John
    O'Donoghue, Brian
    Owens, Elizabeth
    Renwick, Laoise
    Madigan, Kevin
    Kinsella, Anthony
    Clarke, Mary
    Turner, Niall
    O'Callaghan, Eadbhard
    Affiliation
    DETECT Services, Avila House, Block 5 Blackrock Business Park, Blackrock, Co Dublin, Ireland. johnlyne@mail.com
    Issue Date
    2012-03
    Keywords
    BIPOLAR DISORDER
    DIAGNOSIS
    EPIDEMIOLOGY
    DEPRESSIVE DISORDER
    PSYCHIATRIC STATUS RATING SCALES
    PSYCHOTIC DISORDERS
    PSYCHOSIS
    SCHIZOPHRENIA
    IRELAND
    PREVALENCE
    MeSH
    Adolescent
    Adult
    Aged
    Bipolar Disorder
    Depressive Disorder, Major
    Female
    Humans
    Ireland
    Male
    Middle Aged
    Prevalence
    Psychiatric Status Rating Scales
    Psychotic Disorders
    Retrospective Studies
    Schizophrenia
    Schizophrenia, Paranoid
    Severity of Illness Index
    Young Adult
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    Citation
    Prevalence of item level negative symptoms in first episode psychosis diagnoses. 2012, 135 (1-3):128-33 Schizophr. Res.
    Journal
    Schizophrenia research
    URI
    http://hdl.handle.net/10147/265455
    DOI
    10.1016/j.schres.2012.01.004
    PubMed ID
    22281102
    Abstract
    The relevance of negative symptoms across the diagnostic spectrum of the psychoses remains uncertain. The purpose of this study was to report on prevalence of item and subscale level negative symptoms across the first episode psychosis (FEP) diagnostic spectrum in an epidemiological sample, and to ascertain whether items and subscales were more prevalent in a schizophrenia spectrum diagnoses group compared to an 'all other psychotic diagnoses' group. We measured negative symptoms in 330 patients presenting with FEP using the Scale for Assessment of Negative Symptoms (SANS), and ascertained diagnosis using the Structured Clinical Interview for DSM IV. Prevalence of SANS items and subscales were tabulated across all psychotic diagnoses, and logistic regression analysis determined which items and subscales were predictive of schizophrenia spectrum diagnoses. SANS items were most prevalent in schizophrenia spectrum conditions but frequently presented in other FEP diagnoses, particularly substance induced psychotic disorder and Major Depressive Disorder. Brief psychotic disorder and bipolar disorders had low levels of negative symptoms. SANS items and subscales which significantly predicted schizophrenia spectrum diagnoses, were also frequently present in some of the other psychotic diagnoses. Conclusions: SANS items have high prevalence in FEP, and while commonest in schizophrenia spectrum conditions are not restricted to this diagnostic subgroup.
    Item Type
    Article
    Language
    en
    ISSN
    1573-2509
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.schres.2012.01.004
    Scopus Count
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    Saint John of God Hospitaller Services

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