AffiliationDepartment of Dermatology, The Children's University Hospital, Temple St, Dublin 1.
Lupus Erythematosus, Systemic
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CitationRings in the neonate. 2011, 104 (2):52-3 Ir Med J
JournalIrish medical journal
AbstractNeonatal lupus erythematosus (NLE) is an uncommon disease of the neonate. It is believed to be caused by the transplacental passage of maternal autoantibodies to the ribonucleoproteins (Ro/SSA, La/SSB or rarely U RNP) as these are almost invariably present in NLE sera. The most common clinical manifestations include cutaneous lupus lesions and congenital complete heart block. Hepatobiliary and haematologic abnormalities are reported less frequently. We describe a patient with cutaneous NLE to illustrate and raise awareness of the characteristic annular eruption of this condition. We also emphasize the need for thorough investigation for concomitant organ involvement and for maternal education regarding risk in future pregnancies.
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