Challenges with current inhaled treatments for chronic Pseudomonas aeruginosa infection in patients with cystic fibrosis.
Affiliation
National Children's Hospital, Tallaght, Dublin, Ireland. Peter.Greally@amnch.ieIssue Date
2012-06MeSH
Administration, InhalationAnti-Bacterial Agents
Chronic Disease
Cystic Fibrosis
Drug Resistance, Bacterial
Humans
Models, Biological
Pseudomonas Infections
Pseudomonas aeruginosa
Respiratory Tract Infections
Metadata
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Challenges with current inhaled treatments for chronic Pseudomonas aeruginosa infection in patients with cystic fibrosis. 2012, 28 (6):1059-67 Curr Med Res OpinPublisher
Current medical research and opinionJournal
Current medical research and opinionDOI
10.1185/03007995.2012.674500PubMed ID
22401602Abstract
Pseudomonas aeruginosa (Pa) is the predominant pathogen infecting the airways of patients with cystic fibrosis (CF). Initial colonization is usually transient and associated with non-mucoid strains, which can be eradicated if identified early. This strategy can prevent, or at least delay, chronic Pa infection, which eventually develops in the majority of patients by their late teens or early adulthood. This article discusses the management and latest treatment developments of Pa lung infection in patients with CF, with a focus on nebulized antibiotic therapy.Item Type
ArticleLanguage
enISSN
1473-4877ae974a485f413a2113503eed53cd6c53
10.1185/03007995.2012.674500
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