HLA associations reveal genetic heterogeneity in psoriatic arthritis and in the psoriasis phenotype.
Greenberg, David A
AffiliationColumbia University, New York, New York 10032, USA. firstname.lastname@example.org
Genetic Association Studies
Genetic Predisposition to Disease
MetadataShow full item record
CitationHLA associations reveal genetic heterogeneity in psoriatic arthritis and in the psoriasis phenotype. 2012, 64 (4):1134-44 Arthritis Rheum.
PublisherArthritis and rheumatism
JournalArthritis and rheumatism
AbstractRigorously ascertained cases of psoriatic arthritis in subjects presenting to a rheumatology unit were compared with cases of psoriasis in subjects presenting to a dermatology unit, where subjects with musculoskeletal features were excluded, to address 1) the extent to which the contribution of the major histocompatibility complex (MHC) to psoriatic arthritis susceptibility resembles that in psoriasis, and 2) whether MHC genes determine quantitative traits within the psoriatic arthritis phenotype.
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