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    Immune profile and Epstein-Barr virus infection in acute interstitial nephritis: an immunohistochemical study in 78 patients.

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    Authors
    Mansur, Abdurrezagh
    Little, Mark A
    Oh, Weng Chin
    Jacques, Steven
    Nightingale, Peter
    Howie, Alexander J
    Savage, Caroline O S
    Affiliation
    Renal Immunobiology, University of Birmingham, College of Medical and Dental Sciences, London, UK.
    Issue Date
    2011
    MeSH
    Acute Disease
    Adolescent
    Adult
    Aged
    Aged, 80 and over
    Antigens, CD
    Antigens, Differentiation, Myelomonocytic
    Chemokine CCL11
    Creatinine
    Eosinophils
    Epstein-Barr Virus Infections
    Female
    Herpesvirus 4, Human
    Humans
    Interleukin-4
    Kidney
    Macrophages
    Male
    Middle Aged
    Nephritis, Interstitial
    RNA, Viral
    Receptors, CCR3
    Receptors, CCR4
    Retrospective Studies
    Th2 Cells
    Vascular Cell Adhesion Molecule-1
    Viral Matrix Proteins
    Young Adult
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    Citation
    Immune profile and Epstein-Barr virus infection in acute interstitial nephritis: an immunohistochemical study in 78 patients. 2011, 119 (4):c293-300 Nephron Clin Pract
    Publisher
    Nephron. Clinical practice
    Journal
    Nephron. Clinical practice
    URI
    http://hdl.handle.net/10147/253863
    DOI
    10.1159/000329671
    PubMed ID
    21952467
    Abstract
    Acute interstitial nephritis (AIN) is a common cause of acute kidney injury and is characterised by a dense interstitial cellular infiltrate, which has not been well defined. Previous studies have demonstrated a correlation between Epstein-Barr virus (EBV) infection and AIN. The purpose of our study was to define the nature of the interstitial immune infiltrate and to investigate the possibility of renal infection with EBV.
    Item Type
    Article
    Language
    en
    ISSN
    1660-2110
    ae974a485f413a2113503eed53cd6c53
    10.1159/000329671
    Scopus Count
    Collections
    Tallaght University Hospital

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