Immune profile and Epstein-Barr virus infection in acute interstitial nephritis: an immunohistochemical study in 78 patients.
Little, Mark A
Oh, Weng Chin
Howie, Alexander J
Savage, Caroline O S
AffiliationRenal Immunobiology, University of Birmingham, College of Medical and Dental Sciences, London, UK.
Aged, 80 and over
Antigens, Differentiation, Myelomonocytic
Epstein-Barr Virus Infections
Herpesvirus 4, Human
Vascular Cell Adhesion Molecule-1
Viral Matrix Proteins
MetadataShow full item record
CitationImmune profile and Epstein-Barr virus infection in acute interstitial nephritis: an immunohistochemical study in 78 patients. 2011, 119 (4):c293-300 Nephron Clin Pract
PublisherNephron. Clinical practice
JournalNephron. Clinical practice
AbstractAcute interstitial nephritis (AIN) is a common cause of acute kidney injury and is characterised by a dense interstitial cellular infiltrate, which has not been well defined. Previous studies have demonstrated a correlation between Epstein-Barr virus (EBV) infection and AIN. The purpose of our study was to define the nature of the interstitial immune infiltrate and to investigate the possibility of renal infection with EBV.