Immune profile and Epstein-Barr virus infection in acute interstitial nephritis: an immunohistochemical study in 78 patients.

Authors
Mansur, Abdurrezagh
Little, Mark A
Oh, Weng Chin
Jacques, Steven
Nightingale, Peter
Howie, Alexander J
Savage, Caroline O S
Affiliation
Renal Immunobiology, University of Birmingham, College of Medical and Dental Sciences, London, UK.
Issue Date
2011
MeSH
Acute Disease
Adolescent
Adult
Aged
Aged, 80 and over
Antigens, CD
Antigens, Differentiation, Myelomonocytic
Chemokine CCL11
Creatinine
Eosinophils
Epstein-Barr Virus Infections
Female
Herpesvirus 4, Human
Humans
Interleukin-4
Kidney
Macrophages
Male
Middle Aged
Nephritis, Interstitial
RNA, Viral
Receptors, CCR3
Receptors, CCR4
Retrospective Studies
Th2 Cells
Vascular Cell Adhesion Molecule-1
Viral Matrix Proteins
Young Adult

Metadata
Show full item record
Citation
Immune profile and Epstein-Barr virus infection in acute interstitial nephritis: an immunohistochemical study in 78 patients. 2011, 119 (4):c293-300 Nephron Clin Pract
Publisher
Nephron. Clinical practice
Journal
Nephron. Clinical practice
URI
http://hdl.handle.net/10147/253863
DOI
10.1159/000329671
PubMed ID
21952467
Abstract
Acute interstitial nephritis (AIN) is a common cause of acute kidney injury and is characterised by a dense interstitial cellular infiltrate, which has not been well defined. Previous studies have demonstrated a correlation between Epstein-Barr virus (EBV) infection and AIN. The purpose of our study was to define the nature of the interstitial immune infiltrate and to investigate the possibility of renal infection with EBV.
Item Type
Article
Language
en
ISSN
1660-2110
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