Genetically distinct subsets within ANCA-associated vasculitis.
dc.contributor.author | Lyons, Paul A | |
dc.contributor.author | Rayner, Tim F | |
dc.contributor.author | Trivedi, Sapna | |
dc.contributor.author | Holle, Julia U | |
dc.contributor.author | Watts, Richard A | |
dc.contributor.author | Jayne, David R W | |
dc.contributor.author | Baslund, Bo | |
dc.contributor.author | Brenchley, Paul | |
dc.contributor.author | Bruchfeld, Annette | |
dc.contributor.author | Chaudhry, Afzal N | |
dc.contributor.author | Cohen Tervaert, Jan Willem | |
dc.contributor.author | Deloukas, Panos | |
dc.contributor.author | Feighery, Conleth | |
dc.contributor.author | Gross, Wolfgang L | |
dc.contributor.author | Guillevin, Loic | |
dc.contributor.author | Gunnarsson, Iva | |
dc.contributor.author | Harper, Lorraine | |
dc.contributor.author | Hrušková, Zdenka | |
dc.contributor.author | Little, Mark A | |
dc.contributor.author | Martorana, Davide | |
dc.contributor.author | Neumann, Thomas | |
dc.contributor.author | Ohlsson, Sophie | |
dc.contributor.author | Padmanabhan, Sandosh | |
dc.contributor.author | Pusey, Charles D | |
dc.contributor.author | Salama, Alan D | |
dc.contributor.author | Sanders, Jan-Stephan F | |
dc.contributor.author | Savage, Caroline O | |
dc.contributor.author | Segelmark, Mårten | |
dc.contributor.author | Stegeman, Coen A | |
dc.contributor.author | Tesař, Vladimir | |
dc.contributor.author | Vaglio, Augusto | |
dc.contributor.author | Wieczorek, Stefan | |
dc.contributor.author | Wilde, Benjamin | |
dc.contributor.author | Zwerina, Jochen | |
dc.contributor.author | Rees, Andrew J | |
dc.contributor.author | Clayton, David G | |
dc.contributor.author | Smith, Kenneth G C | |
dc.date.accessioned | 2012-11-28T15:29:04Z | |
dc.date.available | 2012-11-28T15:29:04Z | |
dc.date.issued | 2012-07-19 | |
dc.identifier.citation | Genetically distinct subsets within ANCA-associated vasculitis. 2012, 367 (3):214-23 N. Engl. J. Med. | en_GB |
dc.identifier.issn | 1533-4406 | |
dc.identifier.pmid | 22808956 | |
dc.identifier.doi | 10.1056/NEJMoa1108735 | |
dc.identifier.uri | http://hdl.handle.net/10147/253772 | |
dc.description.abstract | Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is a severe condition encompassing two major syndromes: granulomatosis with polyangiitis (formerly known as Wegener's granulomatosis) and microscopic polyangiitis. Its cause is unknown, and there is debate about whether it is a single disease entity and what role ANCA plays in its pathogenesis. We investigated its genetic basis. | |
dc.language.iso | en | en |
dc.publisher | The New England journal of medicine | en_GB |
dc.rights | Archived with thanks to The New England journal of medicine | en_GB |
dc.subject.mesh | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | |
dc.subject.mesh | Case-Control Studies | |
dc.subject.mesh | Female | |
dc.subject.mesh | Genetic Predisposition to Disease | |
dc.subject.mesh | Genome-Wide Association Study | |
dc.subject.mesh | Genotyping Techniques | |
dc.subject.mesh | HLA-DP Antigens | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Major Histocompatibility Complex | |
dc.subject.mesh | Male | |
dc.subject.mesh | Microscopic Polyangiitis | |
dc.subject.mesh | Myeloblastin | |
dc.subject.mesh | Polymorphism, Single Nucleotide | |
dc.subject.mesh | Risk Factors | |
dc.subject.mesh | Wegener Granulomatosis | |
dc.subject.mesh | alpha 1-Antitrypsin | |
dc.title | Genetically distinct subsets within ANCA-associated vasculitis. | en_GB |
dc.type | Article In Press | en |
dc.contributor.department | Cambridge Institute for Medical Research, and Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, United Kingdom. kgcs2@cam.ac.uk | en_GB |
dc.identifier.journal | The New England journal of medicine | en_GB |
dc.description.province | Leinster | en |
html.description.abstract | Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is a severe condition encompassing two major syndromes: granulomatosis with polyangiitis (formerly known as Wegener's granulomatosis) and microscopic polyangiitis. Its cause is unknown, and there is debate about whether it is a single disease entity and what role ANCA plays in its pathogenesis. We investigated its genetic basis. |