Increased spontaneous apoptosis, but not survivin expression, is associated with histomorphologic response to neoadjuvant chemoradiation in rectal cancer.
dc.contributor.author | McDowell, Dermot T | |
dc.contributor.author | Smith, Fraser M | |
dc.contributor.author | Reynolds, John V | |
dc.contributor.author | Maher, Stephen G | |
dc.contributor.author | Adida, Collette | |
dc.contributor.author | Crotty, Paul | |
dc.contributor.author | Gaffney, Eoin F | |
dc.contributor.author | Hollywood, Donal | |
dc.contributor.author | Mehigan, Brian | |
dc.contributor.author | Stephens, Richard B | |
dc.contributor.author | Kennedy, M J | |
dc.date.accessioned | 2012-11-20T16:45:53Z | |
dc.date.available | 2012-11-20T16:45:53Z | |
dc.date.issued | 2009-11 | |
dc.identifier.citation | Increased spontaneous apoptosis, but not survivin expression, is associated with histomorphologic response to neoadjuvant chemoradiation in rectal cancer. 2009, 24 (11):1261-9 Int J Colorectal Dis | en_GB |
dc.identifier.issn | 1432-1262 | |
dc.identifier.pmid | 19593573 | |
dc.identifier.doi | 10.1007/s00384-009-0755-6 | |
dc.identifier.uri | http://hdl.handle.net/10147/252785 | |
dc.description.abstract | Survivin has been shown to be an important mediator of cellular radioresistance in vitro. This study aims to compare survivin expression and apoptosis to histomorphologic responses to neoadjuvant radiochemotherapy (RCT) in rectal cancer. | |
dc.language.iso | en | en |
dc.publisher | International journal of colorectal disease | en_GB |
dc.rights | Archived with thanks to International journal of colorectal disease | en_GB |
dc.subject.mesh | Apoptosis | |
dc.subject.mesh | Biopsy | |
dc.subject.mesh | Cell Proliferation | |
dc.subject.mesh | Chemotherapy, Adjuvant | |
dc.subject.mesh | Gene Expression Regulation, Neoplastic | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Inhibitor of Apoptosis Proteins | |
dc.subject.mesh | Ki-67 Antigen | |
dc.subject.mesh | Lymph Nodes | |
dc.subject.mesh | Microtubule-Associated Proteins | |
dc.subject.mesh | Neoadjuvant Therapy | |
dc.subject.mesh | Neoplasm Staging | |
dc.subject.mesh | Radiotherapy, Adjuvant | |
dc.subject.mesh | Rectal Neoplasms | |
dc.subject.mesh | Staining and Labeling | |
dc.title | Increased spontaneous apoptosis, but not survivin expression, is associated with histomorphologic response to neoadjuvant chemoradiation in rectal cancer. | en_GB |
dc.type | Article | en |
dc.contributor.department | Department of Academic Surgery, St James's Hospital, Dublin, Ireland. | en_GB |
dc.identifier.journal | International journal of colorectal disease | en_GB |
dc.description.province | Leinster | en |
html.description.abstract | Survivin has been shown to be an important mediator of cellular radioresistance in vitro. This study aims to compare survivin expression and apoptosis to histomorphologic responses to neoadjuvant radiochemotherapy (RCT) in rectal cancer. |