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    Identification of risks associated with the prescribing and dispensing of oral anticancer medicines in Ireland.

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    Authors
    Hammond, Lisa
    Marsden, Elaine
    O'Hanlon, Niamh
    King, Fionnuala
    Henman, Martin Charles
    Keane, Claire
    Affiliation
    Pharmacy Department, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland, l.hammond@st-vincents.ie.
    Issue Date
    2012-09-09
    
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    Citation
    Identification of risks associated with the prescribing and dispensing of oral anticancer medicines in Ireland. 2012: Int J Clin Pharm
    Journal
    International journal of clinical pharmacy
    URI
    http://hdl.handle.net/10147/244943
    DOI
    10.1007/s11096-012-9688-1
    PubMed ID
    22961608
    Abstract
    Background Oral anticancer medicines (OAM) facilitate transfer of cancer care into the community, where safeguards developed in hospitals that control their prescribing, dispensing and administration may not exist. Objective To determine if the systems of prescribing and dispensing OAM in Ireland facilitate clinical verification of the prescription, thereby ensuring treatment is tailored and appropriate for the patient. Setting Randomly selected community pharmacies in Ireland and all Irish hospitals with cancer services. Method A questionnaire was sent to a random selection of Irish community pharmacists. A different questionnaire was sent to all Irish hospitals treating cancer patients. One hundred OAM prescriptions were retrospectively reviewed, to assess the information presented and the potential barriers to a community pharmacist performing a clinical verification of the prescription. Main outcome measure Community pharmacist survey: problems experienced when dispensing OAM and risk factors identified with the current system. Hospital pharmacist survey: proportion of hospitals that clinically verify prescriptions for parenteral versus oral anticancer medicines and associated policies. OAM prescription review: proportion of OAM prescriptions that contained sufficient information for a community pharmacist to clinically verify the prescription and safely dispense the medication. Results Sixty-four percent of community pharmacist respondents felt they did not have enough information available to them to safely dispense these prescriptions, and 74 % felt that patients are at risk with the current Irish system of prescribing and dispensing OAM. Irish hospitals do not have systems to ensure that all OAM prescriptions are clinically verified by a pharmacist. Seventeen different agents were prescribed on the prescriptions reviewed. The information provided to the community pharmacist would have allowed them to clinically verify 7 % of the OAM prescriptions. Conclusion Prescriptions for OAM reach the community pharmacist with little chance that they have been clinically verified in the hospital and the medicine reaches the patient with little chance that the community pharmacist has been able to clinically verify it. Healthcare risks are increased when inadequate information about patients and their medicines are available. Appropriate specialist practitioners should be provided nationally to clinically oversee each stage of the OAM use process.
    Item Type
    Article
    Language
    en
    ISSN
    2210-7711
    ae974a485f413a2113503eed53cd6c53
    10.1007/s11096-012-9688-1
    Scopus Count
    Collections
    St. Vincent's University Hospital

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