Obstetric outcome with low molecular weight heparin therapy during pregnancy.
dc.contributor.author | Donnelly, J | |
dc.contributor.author | Byrne, J | |
dc.contributor.author | Murphy, K | |
dc.contributor.author | McAuliffe, F | |
dc.date.accessioned | 2012-07-11T13:19:26Z | |
dc.date.available | 2012-07-11T13:19:26Z | |
dc.date.issued | 2012-01 | |
dc.identifier.citation | Obstetric outcome with low molecular weight heparin therapy during pregnancy. 2012, 105 (1):27-9 Ir Med J | en_GB |
dc.identifier.issn | 0332-3102 | |
dc.identifier.pmid | 22397211 | |
dc.identifier.uri | http://hdl.handle.net/10147/233211 | |
dc.description.abstract | This was a prospective study of women attending a combined haematology/obstetric antenatal clinic in the National Maternity Hospital (2002-2008). Obstetric outcome in mothers treated with low molecular weight heparin (LMWH) was compared to the general obstetric population of 2006. There were 133 pregnancies in 105 women. 85 (63.9%) received prophylactic LMWH and 38 (28.6%) received therapeutic LMWH in pregnancy. 10 (7.5%) received postpartum prophylaxis only. The perinatal mortality rate was 7.6/1000 births. 14 (11.3%) women delivered preterm which is significantly higher than the hospital population rate (5.7%, p<0.05). Despite significantly higher labour induction rates (50% vs 29.2% p<0.01), there was no difference in CS rates compared to the general hospital population (15.4% vs 18.9%, NS). If carefully managed, these high-risk women can achieve similar vaginal delivery rates as the general obstetric population. | |
dc.language.iso | en | en |
dc.publisher | Irish Medical Journal (IMJ) | en_GB |
dc.relation.url | http://www.ncbi.nlm.nih.gov/pubmed/22397211 | en_GB |
dc.rights | Archived with thanks to Irish medical journal | en_GB |
dc.subject.mesh | Adult | |
dc.subject.mesh | Anticoagulants | |
dc.subject.mesh | Chi-Square Distribution | |
dc.subject.mesh | Female | |
dc.subject.mesh | Heparin, Low-Molecular-Weight | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Ireland | |
dc.subject.mesh | Pregnancy | |
dc.subject.mesh | Pregnancy Complications, Cardiovascular | |
dc.subject.mesh | Pregnancy Outcome | |
dc.subject.mesh | Risk Factors | |
dc.subject.mesh | Venous Thrombosis | |
dc.title | Obstetric outcome with low molecular weight heparin therapy during pregnancy. | en_GB |
dc.type | Article | en |
dc.contributor.department | Department of Obstetrics and Gynaecology, National Maternity Hospital, Holles St, Dublin 2. jenniferdonnelly@mac.com | en_GB |
dc.identifier.journal | Irish medical journal | en_GB |
dc.description.province | Leinster | en |
refterms.dateFOA | 2018-08-22T18:00:10Z | |
html.description.abstract | This was a prospective study of women attending a combined haematology/obstetric antenatal clinic in the National Maternity Hospital (2002-2008). Obstetric outcome in mothers treated with low molecular weight heparin (LMWH) was compared to the general obstetric population of 2006. There were 133 pregnancies in 105 women. 85 (63.9%) received prophylactic LMWH and 38 (28.6%) received therapeutic LMWH in pregnancy. 10 (7.5%) received postpartum prophylaxis only. The perinatal mortality rate was 7.6/1000 births. 14 (11.3%) women delivered preterm which is significantly higher than the hospital population rate (5.7%, p<0.05). Despite significantly higher labour induction rates (50% vs 29.2% p<0.01), there was no difference in CS rates compared to the general hospital population (15.4% vs 18.9%, NS). If carefully managed, these high-risk women can achieve similar vaginal delivery rates as the general obstetric population. |