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dc.contributor.authorDonnelly, J
dc.contributor.authorByrne, J
dc.contributor.authorMurphy, K
dc.contributor.authorMcAuliffe, F
dc.date.accessioned2012-07-11T13:19:26Z
dc.date.available2012-07-11T13:19:26Z
dc.date.issued2012-01
dc.identifier.citationObstetric outcome with low molecular weight heparin therapy during pregnancy. 2012, 105 (1):27-9 Ir Med Jen_GB
dc.identifier.issn0332-3102
dc.identifier.pmid22397211
dc.identifier.urihttp://hdl.handle.net/10147/233211
dc.description.abstractThis was a prospective study of women attending a combined haematology/obstetric antenatal clinic in the National Maternity Hospital (2002-2008). Obstetric outcome in mothers treated with low molecular weight heparin (LMWH) was compared to the general obstetric population of 2006. There were 133 pregnancies in 105 women. 85 (63.9%) received prophylactic LMWH and 38 (28.6%) received therapeutic LMWH in pregnancy. 10 (7.5%) received postpartum prophylaxis only. The perinatal mortality rate was 7.6/1000 births. 14 (11.3%) women delivered preterm which is significantly higher than the hospital population rate (5.7%, p<0.05). Despite significantly higher labour induction rates (50% vs 29.2% p<0.01), there was no difference in CS rates compared to the general hospital population (15.4% vs 18.9%, NS). If carefully managed, these high-risk women can achieve similar vaginal delivery rates as the general obstetric population.
dc.language.isoenen
dc.publisherIrish Medical Journal (IMJ)en_GB
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/22397211en_GB
dc.rightsArchived with thanks to Irish medical journalen_GB
dc.subject.meshAdult
dc.subject.meshAnticoagulants
dc.subject.meshChi-Square Distribution
dc.subject.meshFemale
dc.subject.meshHeparin, Low-Molecular-Weight
dc.subject.meshHumans
dc.subject.meshIreland
dc.subject.meshPregnancy
dc.subject.meshPregnancy Complications, Cardiovascular
dc.subject.meshPregnancy Outcome
dc.subject.meshRisk Factors
dc.subject.meshVenous Thrombosis
dc.titleObstetric outcome with low molecular weight heparin therapy during pregnancy.en_GB
dc.typeArticleen
dc.contributor.departmentDepartment of Obstetrics and Gynaecology, National Maternity Hospital, Holles St, Dublin 2. jenniferdonnelly@mac.comen_GB
dc.identifier.journalIrish medical journalen_GB
dc.description.provinceLeinsteren
refterms.dateFOA2018-08-22T18:00:10Z
html.description.abstractThis was a prospective study of women attending a combined haematology/obstetric antenatal clinic in the National Maternity Hospital (2002-2008). Obstetric outcome in mothers treated with low molecular weight heparin (LMWH) was compared to the general obstetric population of 2006. There were 133 pregnancies in 105 women. 85 (63.9%) received prophylactic LMWH and 38 (28.6%) received therapeutic LMWH in pregnancy. 10 (7.5%) received postpartum prophylaxis only. The perinatal mortality rate was 7.6/1000 births. 14 (11.3%) women delivered preterm which is significantly higher than the hospital population rate (5.7%, p<0.05). Despite significantly higher labour induction rates (50% vs 29.2% p<0.01), there was no difference in CS rates compared to the general hospital population (15.4% vs 18.9%, NS). If carefully managed, these high-risk women can achieve similar vaginal delivery rates as the general obstetric population.


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