Role of the insulin-like growth factor 1 axis and visceral adiposity in oesophageal adenocarcinoma.
dc.contributor.author | Donohoe, C L | |
dc.contributor.author | Doyle, S L | |
dc.contributor.author | McGarrigle, S | |
dc.contributor.author | Cathcart, M C | |
dc.contributor.author | Daly, E | |
dc.contributor.author | O'Grady, A | |
dc.contributor.author | Lysaght, J | |
dc.contributor.author | Pidgeon, G P | |
dc.contributor.author | Reynolds, J V | |
dc.date.accessioned | 2012-06-27T14:39:29Z | |
dc.date.available | 2012-06-27T14:39:29Z | |
dc.date.issued | 2012-03 | |
dc.identifier.citation | Role of the insulin-like growth factor 1 axis and visceral adiposity in oesophageal adenocarcinoma. 2012, 99 (3):387-96 Br J Surg | en_GB |
dc.identifier.issn | 1365-2168 | |
dc.identifier.pmid | 22241325 | |
dc.identifier.doi | 10.1002/bjs.8658 | |
dc.identifier.uri | http://hdl.handle.net/10147/231052 | |
dc.description.abstract | Epidemiological studies have linked obesity with many cancers. The insulin-like growth factor (IGF) 1 axis may be an important mediator in obesity-associated cancer. This study examined the relationship between IGF-1 and its receptor (IGF-1R) in oesophageal adenocarcinoma, a cancer strongly linked to obesity. | |
dc.language.iso | en | en |
dc.rights | Archived with thanks to The British journal of surgery | en_GB |
dc.subject.mesh | Adenocarcinoma | |
dc.subject.mesh | Adult | |
dc.subject.mesh | Aged | |
dc.subject.mesh | Body Mass Index | |
dc.subject.mesh | Enzyme-Linked Immunosorbent Assay | |
dc.subject.mesh | Esophageal Neoplasms | |
dc.subject.mesh | Female | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Immunohistochemistry | |
dc.subject.mesh | Insulin-Like Growth Factor I | |
dc.subject.mesh | Intra-Abdominal Fat | |
dc.subject.mesh | Male | |
dc.subject.mesh | Middle Aged | |
dc.subject.mesh | Obesity, Abdominal | |
dc.subject.mesh | RNA, Messenger | |
dc.subject.mesh | Real-Time Polymerase Chain Reaction | |
dc.subject.mesh | Receptor, IGF Type 1 | |
dc.subject.mesh | Survival Analysis | |
dc.subject.mesh | Waist Circumference | |
dc.title | Role of the insulin-like growth factor 1 axis and visceral adiposity in oesophageal adenocarcinoma. | en_GB |
dc.type | Article | en |
dc.contributor.department | Department of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin/St James's Hospital, Dublin, Ireland. | en_GB |
dc.identifier.journal | The British journal of surgery | en_GB |
dc.description.province | Leinster | en |
html.description.abstract | Epidemiological studies have linked obesity with many cancers. The insulin-like growth factor (IGF) 1 axis may be an important mediator in obesity-associated cancer. This study examined the relationship between IGF-1 and its receptor (IGF-1R) in oesophageal adenocarcinoma, a cancer strongly linked to obesity. |