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dc.contributor.authorDonohoe, C L
dc.contributor.authorDoyle, S L
dc.contributor.authorMcGarrigle, S
dc.contributor.authorCathcart, M C
dc.contributor.authorDaly, E
dc.contributor.authorO'Grady, A
dc.contributor.authorLysaght, J
dc.contributor.authorPidgeon, G P
dc.contributor.authorReynolds, J V
dc.date.accessioned2012-06-27T14:39:29Z
dc.date.available2012-06-27T14:39:29Z
dc.date.issued2012-03
dc.identifier.citationRole of the insulin-like growth factor 1 axis and visceral adiposity in oesophageal adenocarcinoma. 2012, 99 (3):387-96 Br J Surgen_GB
dc.identifier.issn1365-2168
dc.identifier.pmid22241325
dc.identifier.doi10.1002/bjs.8658
dc.identifier.urihttp://hdl.handle.net/10147/231052
dc.description.abstractEpidemiological studies have linked obesity with many cancers. The insulin-like growth factor (IGF) 1 axis may be an important mediator in obesity-associated cancer. This study examined the relationship between IGF-1 and its receptor (IGF-1R) in oesophageal adenocarcinoma, a cancer strongly linked to obesity.
dc.language.isoenen
dc.rightsArchived with thanks to The British journal of surgeryen_GB
dc.subject.meshAdenocarcinoma
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshBody Mass Index
dc.subject.meshEnzyme-Linked Immunosorbent Assay
dc.subject.meshEsophageal Neoplasms
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshImmunohistochemistry
dc.subject.meshInsulin-Like Growth Factor I
dc.subject.meshIntra-Abdominal Fat
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshObesity, Abdominal
dc.subject.meshRNA, Messenger
dc.subject.meshReal-Time Polymerase Chain Reaction
dc.subject.meshReceptor, IGF Type 1
dc.subject.meshSurvival Analysis
dc.subject.meshWaist Circumference
dc.titleRole of the insulin-like growth factor 1 axis and visceral adiposity in oesophageal adenocarcinoma.en_GB
dc.typeArticleen
dc.contributor.departmentDepartment of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin/St James's Hospital, Dublin, Ireland.en_GB
dc.identifier.journalThe British journal of surgeryen_GB
dc.description.provinceLeinsteren
html.description.abstractEpidemiological studies have linked obesity with many cancers. The insulin-like growth factor (IGF) 1 axis may be an important mediator in obesity-associated cancer. This study examined the relationship between IGF-1 and its receptor (IGF-1R) in oesophageal adenocarcinoma, a cancer strongly linked to obesity.


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