Show simple item record

dc.contributor.authorBasit, I
dc.contributor.authorJohnson, S N
dc.contributor.authorMocanu, E
dc.contributor.authorGeary, M
dc.contributor.authorDaly, S
dc.contributor.authorWingfield, M
dc.date.accessioned2012-06-12T11:24:54Z
dc.date.available2012-06-12T11:24:54Z
dc.date.issued2012-03
dc.identifier.citationMode of conception of triplets and high order multiple pregnancies. 2012, 105 (3):80-3 Ir Med Jen_GB
dc.identifier.issn0332-3102
dc.identifier.pmid22558814
dc.identifier.urihttp://hdl.handle.net/10147/228572
dc.description.abstractA retrospective audit was performed of all high order multiple pregnancies (HOMPs) delivered in three maternity hospitals in Dublin between 1999 and 2008. The mode of conception for each pregnancy was established with a view to determining means of reducing their incidence. A total of 101 HOMPs occurred, 93 triplet, 7 quadruplet and 1 quintuplet. Information regarding the mode of conception was available for 78 (81%) pregnancies. Twenty eight (27.7%) were spontaneous, 34 (33.7%) followedlVF/ICSI/FET treatment (in-vitro fertilisation, intracytoplasmic sperm injection, frozen embryo transfer), 16 (15.8%) resulted from Clomiphene Citrate treatment and 6 (6%) followed ovulation induction with gonadotrophins. Triplet and HOMPs are a major cause of maternal, feta land neonatal morbidity. Many are iatrogenic, arising from fertility treatments including Clomiphene. Reducing the numbers of embryos transferred will address IVF/ICSI/FET-related multiple pregnancy rates and this is currently happening in Ireland. Clomiphene and gonadotrophins should only be prescribed when appropriate resources are available to monitor patients adequately.
dc.language.isoenen
dc.rightsArchived with thanks to Irish medical journalen_GB
dc.subject.meshFemale
dc.subject.meshFertilization
dc.subject.meshHumans
dc.subject.meshIreland
dc.subject.meshPregnancy
dc.subject.meshPregnancy, Multiple
dc.subject.meshReproductive Techniques, Assisted
dc.subject.meshRetrospective Studies
dc.titleMode of conception of triplets and high order multiple pregnancies.en_GB
dc.typeArticleen
dc.contributor.departmentDepartment of Obstetrics and Gynaecology, Coombe Women and Infant's University Hospital, Cork St., Dublin. irambasit@hotmail.comen_GB
dc.identifier.journalIrish medical journalen_GB
dc.description.provinceLeinsteren
html.description.abstractA retrospective audit was performed of all high order multiple pregnancies (HOMPs) delivered in three maternity hospitals in Dublin between 1999 and 2008. The mode of conception for each pregnancy was established with a view to determining means of reducing their incidence. A total of 101 HOMPs occurred, 93 triplet, 7 quadruplet and 1 quintuplet. Information regarding the mode of conception was available for 78 (81%) pregnancies. Twenty eight (27.7%) were spontaneous, 34 (33.7%) followedlVF/ICSI/FET treatment (in-vitro fertilisation, intracytoplasmic sperm injection, frozen embryo transfer), 16 (15.8%) resulted from Clomiphene Citrate treatment and 6 (6%) followed ovulation induction with gonadotrophins. Triplet and HOMPs are a major cause of maternal, feta land neonatal morbidity. Many are iatrogenic, arising from fertility treatments including Clomiphene. Reducing the numbers of embryos transferred will address IVF/ICSI/FET-related multiple pregnancy rates and this is currently happening in Ireland. Clomiphene and gonadotrophins should only be prescribed when appropriate resources are available to monitor patients adequately.


This item appears in the following Collection(s)

Show simple item record