• Chemotherapy for resistant or recurrent gestational trophoblastic neoplasia.

      Alazzam, Mo'iad; Tidy, John; Osborne, Raymond; Coleman, Robert; Hancock, Barry W; Lawrie, Theresa A; Department of Gynaecology, The Galway Clinic, Doughiska, Galway, Ireland. moiad@doctors.org.uk (2012-12)
      Gestational trophoblastic neoplasia (GTN) is a highly curable group of pregnancy-related tumours; however, approximately 25% of GTN tumours will be resistant to, or will relapse after, initial chemotherapy. These resistant and relapsed lesions will require salvage chemotherapy with or without surgery. Various salvage regimens are used worldwide. It is unclear which regimens are the most effective and the least toxic.
    • First-line chemotherapy in low-risk gestational trophoblastic neoplasia.

      Alazzam, Mo'iad; Tidy, John; Hancock, Barry W; Osborne, Raymond; Lawrie, Theresa A; Department of Gynaecology, The Galway Clinic, Doughiska, Galway, Ireland. moiad@doctors.org.uk (2012)
      This is an update of a Cochrane review that was first published in Issue 1, 2009. Gestational trophoblastic neoplasia (GTN) is a rare but curable disease arising in the fetal chorion during pregnancy. Most women with low-risk GTN will be cured by evacuation of the uterus with or without single-agent chemotherapy. However, chemotherapy regimens vary between treatment centres worldwide and the comparable benefits and risks of these different regimens are unclear.
    • Galway Clinic annual report 2010

      Galway Clinic (Galway Clinic, 2011)
    • Initial consecutive 125 cases of robotic assisted laparoscopic radical prostatectomy performed in Ireland's first robotic radical prostatectomy centre.

      Bouchier-Hayes, D M; Clancy, K X; Canavan, K; O'Malley, P J; Galway Clinic, Suite 30, Doughiska, Galway, Ireland. davidbouchierhayes@yahoo.co.uk (2012-03)
      We examined the patient characteristics, operative proceedings and the outcomes of the initial series of 125 cases of robot-assisted laparoscopic radical prostatectomy (RALRP) in an independent hospital in Ireland, performed by two surgeons using the da Vinci(®) surgical system.
    • Management and progress of inflammatory joint disease with biological agents and the development of a seamless service

      Bewley, Trish; Phelan, Mark J I (Nursing in General Practice, 2013-05)
      The World Health Organisation and the United Nations designated the first decade of this century as the Decade of Bone and Joint Disease.1 This heralded dramatic and unprecedented changes in the management of inflammatory joint diseases such as rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS) and other disorders.
    • The management of hypertension

      Morris, Aoife; Murphy, Alma; Clarke, John (Nursing in General Practice, 2013-09)
      he World Health Organisation (WHO) describes hypertension as “a condition in which blood vessels have persistently raised pressure”. If left untreated, hypertension can have detrimental effects on health and mortality, leading to preventable incidents such as myocardial infarction, heart failure, stroke and kidney failure. There has been a surge in the prevalence of hypertension worldwide, climbing from six hundred million in 1980 to one billion in 2008 and if appropriate action is not taken, deaths due to cardiovascular disease are projected to rise, according to WHO.
    • Reinforced long saphenous vein bypass graft for infrainguinal reconstruction procedures: case series and literature review.

      Hynes, Niamh; Mahendran, Bhasakarapandian; Tawfik, Sherif; Sultan, Sherif; Department of Vascular & Endovascular Surgery, Galway, Clinic, Doughiska, Co. Galway, Ireland. (Vascular, 2006-03)
      Poor rehabilitation rates and the high-cost of managing postamputation patients justify an aggressive revascularization policy in critical lower limb ischemia. Endovascular therapy is our first choice for limb salvage in these patients. However there are patients for whom endovascular therapy is not feasible. When bypass is necessary, autologous vein is a superior conduit to synthetic material. However, varicosities usually contraindicate autologous vein bypass because of the risk of aneurysm formation, rupture and increased intimal hyperplasia compared with nonvaricose venous grafts. We report the use of varicosed long saphenous vein (LSV) with external Dacron support in infrainguinal bypass procedures for limb salvage, where endovascular therapy was not feasible. The external Dacron tube was not brought close to the distal anastomotic area itself. With a mean follow-up of 18 months, duplex ultrasonography and computed tomography angiography showed no evidence of stenosis of the reinforced vein segments or aneurysmal degeneration of the residual vein. External reinforcement with Dacron prosthesis allows the use of autogenous greater saphenous veins with varicose dilatation without compromising graft patency and limb salvage.
    • Variations in the usage and composition of a radial cocktail during radial access coronary angiography procedures.

      Pate, G; Broderick, B; The Galway Clinic, Doughiska, Galway. gordon.pate@galwayclinic.com (2011-10)
      A survey was conducted of medication administered during radial artery cannulation for coronary angiography in 2009 in Ireland; responses were obtained for 15 of 20 centres, in 5 of which no radial access procedures were undertaken. All 10 (100%) centres which provided data used heparin and one or more anti-spasmodics; verapamil in 9 (90%), nitrate in 1 (10%), both in 2 (20%). There were significant variations in the doses used. Further work needs to be done to determine the optimum cocktail to prevent radial artery injury following coronary angiography.