Atypical presentation of macrophagic myofasciitis 10 years post vaccination.
AffiliationDepartment of Neurology, Cork University Hospital, Cork, Ireland., email@example.com
MeSHAluminum Hydroxide/adverse effects
Anti-Inflammatory Agents/therapeutic use
Histocompatibility Antigens Class II/analysis/metabolism
Immune System/drug effects/physiopathology
Immune System Diseases/*chemically induced/metabolism/physiopathology
Macrophage Activation/*drug effects/physiology
Muscle, Skeletal/*drug effects/pathology/physiopathology
MetadataShow full item record
CitationNeuromuscul Disord. 2006 Dec;16(12):867-9. Epub 2006 Sep 26.
JournalNeuromuscular disorders : NMD
AbstractMacrophagic myofasciitis (MMF) is an uncommon inflammatory disorder of muscle believed to be due to persistence of vaccine-derived aluminium hydroxide at the site of injection. The condition is characterised by diffuse myalgias, arthralgia and fatigue. We describe a patient with histologically confirmed MMF whose presentation was atypical with left chest and upper limb pain beginning more than 10 years post vaccination. Treatment with steroids led to symptomatic improvement. Although rare, clinicians should consider MMF in cases of atypical myalgia.
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