Atypical presentation of macrophagic myofasciitis 10 years post vaccination.
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Affiliation
Department of Neurology, Cork University Hospital, Cork, Ireland., aisling.ryan4@mailp.hse.ieIssue Date
2012-02-03T15:17:35ZMeSH
Aluminum Hydroxide/adverse effectsAnti-Inflammatory Agents/therapeutic use
Female
Histocompatibility Antigens Class II/analysis/metabolism
Humans
Immune System/drug effects/physiopathology
Immune System Diseases/*chemically induced/metabolism/physiopathology
Macrophage Activation/*drug effects/physiology
Middle Aged
Muscle, Skeletal/*drug effects/pathology/physiopathology
Myositis/*chemically induced/metabolism/physiopathology
Steroids/therapeutic use
Time
Time Factors
Vaccination/*adverse effects
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Neuromuscul Disord. 2006 Dec;16(12):867-9. Epub 2006 Sep 26.Journal
Neuromuscular disorders : NMDDOI
10.1016/j.nmd.2006.07.017PubMed ID
17005400Abstract
Macrophagic myofasciitis (MMF) is an uncommon inflammatory disorder of muscle believed to be due to persistence of vaccine-derived aluminium hydroxide at the site of injection. The condition is characterised by diffuse myalgias, arthralgia and fatigue. We describe a patient with histologically confirmed MMF whose presentation was atypical with left chest and upper limb pain beginning more than 10 years post vaccination. Treatment with steroids led to symptomatic improvement. Although rare, clinicians should consider MMF in cases of atypical myalgia.Language
engISSN
0960-8966 (Print)0960-8966 (Linking)
ae974a485f413a2113503eed53cd6c53
10.1016/j.nmd.2006.07.017
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