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dc.contributor.authorPayne, Annen_GB
dc.contributor.authorBarry, Sandraen_GB
dc.contributor.authorCreedon, Brianen_GB
dc.contributor.authorStone, Carolen_GB
dc.contributor.authorSweeney, Catherineen_GB
dc.contributor.authorO' Brien, Tonyen_GB
dc.contributor.authorO' Sullivan, Kathleenen_GB
dc.date.accessioned2012-02-03T15:16:46Z
dc.date.available2012-02-03T15:16:46Z
dc.date.issued2012-02-03T15:16:46Z
dc.identifier.citationPalliat Med. 2007 Apr;21(3):193-8.en_GB
dc.identifier.issn0269-2163 (Print)en_GB
dc.identifier.issn0269-2163 (Linking)en_GB
dc.identifier.pmid17641072en_GB
dc.identifier.doi10.1177/0269216307077315en_GB
dc.identifier.urihttp://hdl.handle.net/10147/209270
dc.description.abstractOBJECTIVES: The primary objective in this study is to determine the sensitivity and specificity of a two-item screening interview for depression versus the formal psychiatric interview, in the setting of a specialist palliative in-patient unit so that we may identify those individuals suffering from depressive disorder and therefore optimise their management in this often-complex population. METHODS: A prospective sample of consecutive admissions (n = 167) consented to partake in the study, and the screening interview was asked separately to the formal psychiatric interview. RESULTS: The two-item questionnaire, achieved a sensitivity of 90.7% (95% CI 76.9-97.0) but a lower specificity of 67.7% (95% CI 58.7-75.7). The false positive rate was 32.3% (95% CI 24.3-41.3), but the false negative rate was found to be a low 9.3% (95% CI 3.0-23.1). A subgroup analysis of individuals with a past experience of depressive illness, (n = 95), revealed that a significant number screened positive for depression by the screening test, 55.2% (16/29) compared to those with no background history of depression, 33.3% (22/66) (P = 0.045). CONCLUSION: The high sensitivity and low false negative rate of the two-question screening tool will aid health professionals in identifying depression in the in-patient specialist palliative care unit. Individuals, who admit to a previous experience of depressive illness, are more likely to respond positively to the two-item questionnaire than those who report no prior history of depressive illness (P = 0.045).
dc.language.isoengen_GB
dc.subject.meshAdulten_GB
dc.subject.meshAgeden_GB
dc.subject.meshAged, 80 and overen_GB
dc.subject.meshChi-Square Distributionen_GB
dc.subject.meshDepression/*diagnosisen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHumansen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMiddle Ageden_GB
dc.subject.meshPalliative Care/*methodsen_GB
dc.subject.meshProspective Studiesen_GB
dc.subject.mesh*Psychiatric Status Rating Scalesen_GB
dc.subject.meshQuestionnairesen_GB
dc.subject.meshSensitivity and Specificityen_GB
dc.titleSensitivity and specificity of a two-question screening tool for depression in a specialist palliative care unit.en_GB
dc.contributor.departmentCork University Hospital, Cork, Ireland. dannann@eircom.neten_GB
dc.identifier.journalPalliative medicineen_GB
dc.description.provinceMunster
html.description.abstractOBJECTIVES: The primary objective in this study is to determine the sensitivity and specificity of a two-item screening interview for depression versus the formal psychiatric interview, in the setting of a specialist palliative in-patient unit so that we may identify those individuals suffering from depressive disorder and therefore optimise their management in this often-complex population. METHODS: A prospective sample of consecutive admissions (n = 167) consented to partake in the study, and the screening interview was asked separately to the formal psychiatric interview. RESULTS: The two-item questionnaire, achieved a sensitivity of 90.7% (95% CI 76.9-97.0) but a lower specificity of 67.7% (95% CI 58.7-75.7). The false positive rate was 32.3% (95% CI 24.3-41.3), but the false negative rate was found to be a low 9.3% (95% CI 3.0-23.1). A subgroup analysis of individuals with a past experience of depressive illness, (n = 95), revealed that a significant number screened positive for depression by the screening test, 55.2% (16/29) compared to those with no background history of depression, 33.3% (22/66) (P = 0.045). CONCLUSION: The high sensitivity and low false negative rate of the two-question screening tool will aid health professionals in identifying depression in the in-patient specialist palliative care unit. Individuals, who admit to a previous experience of depressive illness, are more likely to respond positively to the two-item questionnaire than those who report no prior history of depressive illness (P = 0.045).


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