Tuberculosis due to Mycobacterium bovis in humans in the south-west region of Ireland: is there a relationship with infection prevalence in cattle?
AffiliationDepartment of Respiratory Medicine, Cork University Hospital, Ireland.
MetadataShow full item record
CitationTuber Lung Dis. 1996 Dec;77(6):545-8.
JournalTubercle and lung disease : the official journal of the International Union, against Tuberculosis and Lung Disease
AbstractOBJECTIVE: To compare the incidence of tuberculosis due to Mycobacterium bovis in humans to the prevalence of M. bovis infection in cattle in south-west Ireland and discuss possible links between them. SETTING: In the south-west region of Ireland, a mixed urban and rural community (pop. 536,000), there is a residuum of human tuberculosis caused by M. bovis. METHODS: A retrospective analysis of the incidence of culture-positive M. bovis disease in humans in south-west Ireland from 1983 to 1994 and of the results of tuberculin testing in cattle from 1978 to 1994 for the same region. RESULTS: One to five cases of human tuberculosis due to M. bovis were recorded per year while the overall prevalence of bovine infection fell gradually during the period of study from 467 tuberculin-positive animals per 100,000 cattle tested in 1983 to 158 per 100,000 in 1994. CONCLUSION: The low incidence plateau of human tuberculosis due to M. bovis together with the decline in prevalence of animal infection in the overall period studied suggest a cut-off in the animal to human chain of infection at two points; the animal source and the ingestion of (now pasteurized) milk. This would suggest that disease in humans is now due to reactivation of previous foci of infection which were acquired when milk pasteurization was not compulsory. Based on this, we would anticipate a further reduction and possible elimination of human tuberculosis due to M. bovis in this region in the next 10-15 years.
- Human Mycobacterium bovis infection in the United Kingdom: Incidence, risks, control measures and review of the zoonotic aspects of bovine tuberculosis.
- Authors: de la Rua-Domenech R
- Issue date: 2006 Mar
- Human Mycobacterium bovis infection in the south-west of Ireland 1983-1992: a comparison with M. tuberculosis.
- Authors: Cotter TP, O'Shaughnessy E, Sheehan S, Cryan B, Bredin CP
- Issue date: 1996 Mar-Apr
- Human tuberculosis caused by Mycobacterium bovis in the United States, Latin America and the Caribbean.
- Authors: de Kantor IN, LoBue PA, Thoen CO
- Issue date: 2010 Nov
- Mycobacterium bovis infection in domestic pigs in Great Britain.
- Authors: Bailey SS, Crawshaw TR, Smith NH, Palgrave CJ
- Issue date: 2013 Nov
- Spatial and temporal analyses of metrics of tuberculosis infection in badgers (Meles meles) from the Republic of Ireland: Trends in apparent prevalence.
- Authors: Byrne AW, Kenny K, Fogarty U, O'Keeffe JJ, More SJ, McGrath G, Teeling M, Martin SW, Dohoo IR
- Issue date: 2015 Dec 1