AffiliationDepartment of Paediatrics, Cork University Hospital, Wilton.
Diabetes Mellitus, Type 1/*drug therapy
MetadataShow full item record
CitationIr Med J. 1997 Jan-Feb;90(1):31-2.
JournalIrish medical journal
AbstractSince 1984, five patients in the cystic fibrosis (CF) clinic at Cork Regional Hospital have developed diabetes mellitus (DM) and were treated with Insulin. None had received systemic corticosteroids but two had high calorie naso-gastric feeding regimes. Two died from lung disease. A fifteen year old boy developed bilateral cataracts. In nine other paediatric CF clinics in the Republic of Ireland (total: 420 patients), three patients have DM, two receiving Insulin. Abnormal glucose tolerance is becoming more common in CF as patients survive longer. The possible role of corticosteroid treatment and intensive carbohydrate feeding regimes in development of glucose intolerance must be considered. DM in CF differs from the usual childhood DM. Regular screening and early Insulin supplementation may be beneficial.
- [Carbohydrate metabolic changes in cystic fibrosis].
- Authors: García-García E, López-Siguero JP, Olveira C, Pérez-Ruiz E, García JM, Pérez-Frías J, Martínez-Valverde A
- Issue date: 1999 Nov 13
- Insulin resistance with altered secretory kinetics and reduced proinsulin in cystic fibrosis patients.
- Authors: Holl RW, Wolf A, Thon A, Bernhard M, Buck C, Missel M, Heinze E, von der Hardt H, Teller WM
- Issue date: 1997 Aug
- Islet autoantibodies and insulin dependent diabetes mellitus in cystic fibrosis.
- Authors: Nousia-Arvanitakis S, Galli-Tsinopoulou A, Dracoulacos D, Karamouzis M, Demitriadou A
- Issue date: 2000 Mar
- [Glucose intolerance and diabetes during cystic fibrosis].
- Authors: Tubiana-Rufi N, Czernichow P
- Issue date: 1991 Apr
- Diabetes mellitus in an adult cystic fibrosis population.
- Authors: Hayes FJ, O'Brien A, O'Brien C, Fitzgerald MX, McKenna MJ
- Issue date: 1995 May-Jun