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    Elevated serum angiotensin converting enzyme levels in metastatic ovarian dysgerminoma.

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    Authors
    Cotter, T P
    Kealy, N P
    Duggan, P F
    Curtain, A
    Bredin, C P
    Affiliation
    Cork University Hospital, Ireland.
    Issue Date
    2012-02-03T15:15:13Z
    MeSH
    Adult
    Disorders of Sex Development/complications/genetics
    Dysgerminoma/enzymology/*secondary/therapy
    Female
    Humans
    Lymphatic Metastasis
    Male
    Ovarian Neoplasms/*pathology
    Peptidyl-Dipeptidase A/*blood
    Tumor Markers, Biological/*blood
    
    Metadata
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    Citation
    Respir Med. 1997 Apr;91(4):237-9.
    Journal
    Respiratory medicine
    URI
    http://hdl.handle.net/10147/209212
    PubMed ID
    9156148
    Abstract
    A case of a 32-year-old XY genotype female is described, presenting with mediastinal and abdominal lymphadenopathy and associated with an elevated serum angiotensin I converting enzyme (SACE) level. Lymph node histology showed a malignant dysgerminoma of ovarian origin. Combined chemotherapy led to a radiological regression of the lymphadenopathy and coincided with a decrease in SACE concentration. The authors suggest that SACE may be a marker for disseminated germinoma tumours and may be useful for monitoring treatment.
    Language
    eng
    ISSN
    0954-6111 (Print)
    0954-6111 (Linking)
    Collections
    Cork University Hospital

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