Elevated serum angiotensin converting enzyme levels in metastatic ovarian dysgerminoma.
Affiliation
Cork University Hospital, Ireland.Issue Date
2012-02-03T15:15:13ZMeSH
AdultDisorders of Sex Development/complications/genetics
Dysgerminoma/enzymology/*secondary/therapy
Female
Humans
Lymphatic Metastasis
Male
Ovarian Neoplasms/*pathology
Peptidyl-Dipeptidase A/*blood
Tumor Markers, Biological/*blood
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Show full item recordCitation
Respir Med. 1997 Apr;91(4):237-9.Journal
Respiratory medicinePubMed ID
9156148Abstract
A case of a 32-year-old XY genotype female is described, presenting with mediastinal and abdominal lymphadenopathy and associated with an elevated serum angiotensin I converting enzyme (SACE) level. Lymph node histology showed a malignant dysgerminoma of ovarian origin. Combined chemotherapy led to a radiological regression of the lymphadenopathy and coincided with a decrease in SACE concentration. The authors suggest that SACE may be a marker for disseminated germinoma tumours and may be useful for monitoring treatment.Language
engISSN
0954-6111 (Print)0954-6111 (Linking)
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