Elevated serum angiotensin converting enzyme levels in metastatic ovarian dysgerminoma.
AffiliationCork University Hospital, Ireland.
Disorders of Sex Development/complications/genetics
Tumor Markers, Biological/*blood
MetadataShow full item record
CitationRespir Med. 1997 Apr;91(4):237-9.
AbstractA case of a 32-year-old XY genotype female is described, presenting with mediastinal and abdominal lymphadenopathy and associated with an elevated serum angiotensin I converting enzyme (SACE) level. Lymph node histology showed a malignant dysgerminoma of ovarian origin. Combined chemotherapy led to a radiological regression of the lymphadenopathy and coincided with a decrease in SACE concentration. The authors suggest that SACE may be a marker for disseminated germinoma tumours and may be useful for monitoring treatment.