New lessons: Classic treatments in convulsive status epilepticus.
Affiliation
Department of Neurology, Cork University Hospital, Cork. howrurenga@yahoo.comIssue Date
2012-02-03T15:14:15ZMeSH
AdultAged
Aged, 80 and over
Anticonvulsants/*therapeutic use
Benzodiazepines/therapeutic use
Clinical Protocols
Diazepam/therapeutic use
Dose-Response Relationship, Drug
Electroencephalography
Female
Humans
Male
Middle Aged
Phenytoin/therapeutic use
Retrospective Studies
Status Epilepticus/*drug therapy
Metadata
Show full item recordCitation
Ir Med J. 2007 Nov-Dec;100(10):618-20.Journal
Irish medical journalPubMed ID
18277730Abstract
Convulsive status epilepticus is a relatively common life-threatening illness requiring prompt intervention. There has been much debate about the appropriate protocol for management of convulsive status epilepticus. Published data on the management of this condition in Ireland is limited. Our aim was to establish if there was a structured, evidence-based or consensus-based protocol being implemented in the management of status epilepticus in our centre. We retrospectively audited all charts with a diagnosis of 'Status Epilepticus' admitted to our hospital from January 1998 to December 2002. A total of 95 episodes of convulsive status epilepticus were recorded. 34 charts were reviewed. Benzodiazepines were the drug class of first choice in 96% of patients. However, the doses of benzodiazepines used varied widely. The most frequent dose of phenytoin used was 1 gram. No one received continuous EEG monitoring during treatment of refractory status epilepticus. Overall mortality was 18%. The results of this study show that there is no consistent protocol was being followed for the management of convulsive status epilepticus in our centre. The drugs of first choice varied between diazepam and lorazepam in most cases. Although phenytoin was used as second line drug, the dose used was frequently suboptimal. We have developed a protocol for the management for convulsive status in our centre.Language
engISSN
0332-3102 (Print)0332-3102 (Linking)
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