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    Visual and anatomical success with short-term macular tamponade and autologous platelet concentrate.

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    Authors
    Mulhern, M G
    Cullinane, A
    Cleary, P E
    Affiliation
    National University of Ireland Cork, Department of Ophthalmology, Cork University, Hospital, Ireland.
    Issue Date
    2012-02-03T15:12:38Z
    MeSH
    Aged
    *Blood Platelets
    Female
    Fluorescein Angiography
    Fluorocarbons/*therapeutic use
    Fundus Oculi
    Humans
    Injections
    Male
    Prospective Studies
    Retinal Perforations/pathology/physiopathology/*therapy
    Sulfur Hexafluoride/*therapeutic use
    Time Factors
    Treatment Outcome
    Visual Acuity/*physiology
    Vitrectomy/methods
    Vitreous Body
    Show allShow less
    
    Metadata
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    Citation
    Graefes Arch Clin Exp Ophthalmol. 2000 Jul;238(7):577-83.
    Journal
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von, Graefes Archiv fur klinische und experimentelle Ophthalmologie
    URI
    http://hdl.handle.net/10147/209114
    PubMed ID
    10955659
    Abstract
    BACKGROUND: This study aimed to determine whether, in eyes treated for macular hole by vitrectomy and autologous platelet injection, short-term tamponade with SF6 gas was as effective as longer tamponade with C3F8 gas. METHODS: Patients in group 1 (n=31) had vitrectomy, injection of platelet concentrate, and 16% C3F8 gas/air exchange. Patients in group 2 (n=31) were similarly treated, except that 23% SF6 gas was used. Group 1 patients were required to posture prone for 2-4 weeks, group 2 for 6 days. RESULTS: All patients had 3 months' follow-up. Postoperatively, visual acuity improved faster in group 2. However, the final mean improvement in logMAR acuity was similar in both groups. Intraocular pressure (IOP) spikes occurred in 12 patients in group 2 and in 17 patients in group 1. Posterior subcapsular cataract (PSCC) occurred in 55% of cases in group 1 and in just 37% in group 2. The rate of anatomical success in group 1 was 96.7%, and in group 2, 93.5% (P=1.0). CONCLUSIONS: The combination of SF6 gas, platelet concentrate, and short-term prone posturing gave a degree of anatomical and visual success comparable to that of the group which had longer tamponade. Although no differences were statistically significant, several trends did emerge; in group 2, patients recovered visual acuity faster, had fewer IOP spikes, and there were fewer cases of PSCC formation.
    Language
    eng
    ISSN
    0721-832X (Print)
    0721-832X (Linking)
    Collections
    Cork University Hospital

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