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    Small intestinal transplantation.

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    Authors
    Quigley, E M
    Affiliation
    Department of Medicine, Cork University Hospital, Central Sciences Building,, Cork, Ireland. e.quigley@ucc.ie
    Issue Date
    2012-02-03T15:11:24Z
    MeSH
    Adult
    Child
    Graft Rejection/complications/drug therapy/prevention & control
    Humans
    Immunosuppressive Agents/therapeutic use
    Infant
    Intestine, Small/*transplantation
    Liver Failure/*etiology/surgery
    Organ Transplantation/*adverse effects/methods/physiology/trends
    Parenteral Nutrition, Total/adverse effects
    Patient Selection
    Sepsis/complications/prevention & control
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    Citation
    Curr Gastroenterol Rep. 2001 Oct;3(5):408-11.
    Journal
    Current gastroenterology reports
    URI
    http://hdl.handle.net/10147/209068
    PubMed ID
    11560798
    Abstract
    The past few years have witnessed a considerable shift in the clinical status of intestinal transplantation. A great deal of experience has been gained at the most active centers, and results comparable with those reported at a similar stage in the development of other solid-organ graft programs are now being achieved by these highly proficient transplant teams. Rejection and its inevitable associate, sepsis, remain ubiquitous, and new immunosuppressant regimes are urgently needed; some may already be on the near horizon. The recent success of isolated intestinal grafts, together with the mortality and morbidity attendant upon the development of advanced liver disease related to total parenteral nutrition, has prompted the bold proposal that patients at risk for this complication should be identified and should receive isolated small bowel grafts before the onset of end-stage hepatic failure. The very fact that such a suggestion has begun to emerge reflects real progress in this challenging field.
    Language
    eng
    ISSN
    1522-8037 (Print)
    1522-8037 (Linking)
    Collections
    Cork University Hospital

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