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    Postoperative changes in visual evoked potentials and cognitive function tests following sevoflurane anaesthesia.

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    Authors
    Iohom, G
    Collins, I
    Murphy, D
    Awad, I
    O'Connor, G
    McCarthy, N
    Shorten, G
    Affiliation
    Department of Anaesthesia and Intensive Care Medicine, Cork University Hospital, and National University of Ireland, Republic of Ireland.
    Issue Date
    2012-02-03T15:10:50Z
    MeSH
    Adolescent
    Adult
    Anesthetics, Inhalation/*pharmacology
    Cognition/*drug effects
    Evoked Potentials, Visual/*drug effects
    Female
    Humans
    Male
    Methyl Ethers/*pharmacology
    Middle Aged
    Postoperative Period
    Prospective Studies
    Psychometrics
    Psychomotor Performance/drug effects
    Reaction Time/drug effects
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    Show full item record
    Citation
    Br J Anaesth. 2001 Dec;87(6):855-9.
    Journal
    British journal of anaesthesia
    URI
    http://hdl.handle.net/10147/209047
    PubMed ID
    11878686
    Abstract
    We tested the hypothesis that minor disturbance of the visual pathway persists following general anaesthesia even when clinical discharge criteria are met. To test this, we measured visual evoked potentials (VEPs) in 13 ASA I or II patients who did not receive any pre-anaesthetic medication and underwent sevoflurane anaesthesia. VEPs were recorded on four occasions, before anaesthesia and at 30, 60, and 90 min after emergence from anaesthesia. Patients completed visual analogue scales (VAS) for sedation and anxiety, a Trieger Dot Test (TDT) and a Digit Symbol Substitution Test (DSST) immediately before each VEP recording. These results were compared using Student's t-test. P<0.05 was considered significant. VEP latency was prolonged (P<0.001) and amplitude diminished (P<0.05) at 30, 60, and 90 min after emergence from anaesthesia, when VAS scores for sedation and anxiety, TDT, and DSST had returned to pre-anaesthetic levels.
    Language
    eng
    ISSN
    0007-0912 (Print)
    0007-0912 (Linking)
    Collections
    Cork University Hospital

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