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    Health-related quality of life in patients with skull base tumours.

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    Authors
    Kelleher, M O
    Fernandes, M F
    Sim, D W
    O'Sullivan, M G
    Affiliation
    Department of Neurosurgery, Cork University Hospital, Cork, Eire, UK.
    Issue Date
    2012-02-03T15:10:46Z
    MeSH
    Adult
    Aged
    Aged, 80 and over
    Female
    Follow-Up Studies
    Humans
    Male
    Middle Aged
    Neuroma, Acoustic/pathology/rehabilitation/surgery
    Prospective Studies
    *Quality of Life
    Questionnaires
    Scotland
    *Sickness Impact Profile
    Skull Base Neoplasms/*rehabilitation/surgery
    Treatment Outcome
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    Citation
    Br J Neurosurg. 2002 Feb;16(1):16-20.
    Journal
    British journal of neurosurgery
    URI
    http://hdl.handle.net/10147/209045
    PubMed ID
    11926460
    Abstract
    The objective of the investigation was to report on the health-related quality of life (HRQoL) of patients diagnosed with skull base tumours using the Short Form Health Survey questionnaire (SF-36). Those patients suffering with vestibular schwannoma were examined to determine the effect facial nerve function had on their quality of life. It took place at the tertiary referral centre at the Department of Clinical Neurosciences, Western General Hospital, Edinburgh. A prospective study of 70 consecutive patients was taken, who harboured the following tumours: 54 vestibular schwannomas, 13 meningiomas, two haemangioblastomas and one hypoglossal schwannoma. Patients were interviewed using the short form 36 (SF-36) questionnaire. Facial nerve function was assessed in those patients who had vestibular schwannomas. The entire cohort of live skull base patients were assessed after a median follow-up time of 38.4 months. Patients with vestibular schwannoma treated conservatively with interval MRI had a quality of life similar to t he normal population. Those who underwent surgery had a significant difference in two of the SF-36 domains. No statistically significant correlation was found at final assessment between the degree of facial nerve functioning and any of the domains of SF-36. Patients with non-vestibular tumours had an impaired HRQoL in seven of the eight domains. Patients with skull base tumours have a significant impairment of their HRQoL. A conservative policy of follow up with interval MRI for patients with small vestibular schwannomas may therefore be more appropriate to preserve their HRQoL. Facial nerve outcome has little influence on quality of life in vestibular schwannoma patients.
    Language
    eng
    ISSN
    0268-8697 (Print)
    0268-8697 (Linking)
    Collections
    Cork University Hospital

    entitlement

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