The effect of aspirin on blood loss and transfusion requirements in patients with femoral neck fractures.
AuthorsManning, Brian J
Cahill, Ronan A
Redmond, H Paul
AffiliationDepartment of Academic Surgery, Cork University Hospital, Wilton, Cork, Ireland. , firstname.lastname@example.org
Aged, 80 and over
Anti-Inflammatory Agents, Non-Steroidal/*adverse effects
*Blood Loss, Surgical
Femoral Neck Fractures/blood/*surgery
MetadataShow full item record
CitationInjury. 2004 Feb;35(2):121-4.
AbstractAlthough it is widely accepted that aspirin will increase the risk of intra- and post-operative bleeding, clinical studies have not consistently supported this assumption. We aimed to assess the effect of pre-operative aspirin on blood loss and transfusion requirements in patients undergoing emergency fixation of femoral neck fractures. A prospective case-control study was undertaken in patients presenting with femoral neck fractures. Parameters recorded included intra-operative blood loss, post-operative blood loss, transfusion requirements and peri-operative reduction in haemoglobin concentration. Of 89 patients presenting with femoral neck fractures 32 were on long-term aspirin therapy. Pre-operative aspirin ingestion did not significantly affect peri-operative blood loss, or change in haemoglobin concentration or haematocrit. However those patients taking aspirin pre-operatively had a significantly lower haemoglobin concentration and haematocrit and were more likely to be anaemic at presentation than those who were not receiving aspirin. Patients taking aspirin were also more likely to receive blood transfusion post-operatively.