The effect of aspirin on blood loss and transfusion requirements in patients with femoral neck fractures.
AuthorsManning, Brian J
Cahill, Ronan A
Redmond, H Paul
AffiliationDepartment of Academic Surgery, Cork University Hospital, Wilton, Cork, Ireland. , email@example.com
Aged, 80 and over
Anti-Inflammatory Agents, Non-Steroidal/*adverse effects
*Blood Loss, Surgical
Femoral Neck Fractures/blood/*surgery
MetadataShow full item record
CitationInjury. 2004 Feb;35(2):121-4.
AbstractAlthough it is widely accepted that aspirin will increase the risk of intra- and post-operative bleeding, clinical studies have not consistently supported this assumption. We aimed to assess the effect of pre-operative aspirin on blood loss and transfusion requirements in patients undergoing emergency fixation of femoral neck fractures. A prospective case-control study was undertaken in patients presenting with femoral neck fractures. Parameters recorded included intra-operative blood loss, post-operative blood loss, transfusion requirements and peri-operative reduction in haemoglobin concentration. Of 89 patients presenting with femoral neck fractures 32 were on long-term aspirin therapy. Pre-operative aspirin ingestion did not significantly affect peri-operative blood loss, or change in haemoglobin concentration or haematocrit. However those patients taking aspirin pre-operatively had a significantly lower haemoglobin concentration and haematocrit and were more likely to be anaemic at presentation than those who were not receiving aspirin. Patients taking aspirin were also more likely to receive blood transfusion post-operatively.
- Blood transfusion requirements in intracapsular femoral neck fractures.
- Authors: Levi N
- Issue date: 1996 Dec
- Pre-operative aspirin decreases platelet aggregation and increases post-operative blood loss--a prospective, randomised, placebo controlled, double-blind clinical trial in 100 patients with chronic stable angina.
- Authors: Kallis P, Tooze JA, Talbot S, Cowans D, Bevan DH, Treasure T
- Issue date: 1994
- Effects of preoperative aspirin and clopidogrel therapy on perioperative blood loss and blood transfusion requirements in patients undergoing off-pump coronary artery bypass graft surgery.
- Authors: Shim JK, Choi YS, Oh YJ, Bang SO, Yoo KJ, Kwak YL
- Issue date: 2007 Jul
- Operative treatment of trochanteric fractures with dynamic hip screw--is perioperative blood transfusion needed?
- Authors: Chua YP, Kwan MK, Saw A
- Issue date: 2005 Jul
- Open simple prostatectomy and blood transfusion in Nairobi.
- Authors: Ngugi PM, Saula PW
- Issue date: 2007 Sep