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    The effect of aspirin on blood loss and transfusion requirements in patients with femoral neck fractures.

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    Authors
    Manning, Brian J
    O'Brien, Noel
    Aravindan, Selvaraj
    Cahill, Ronan A
    McGreal, Gerald
    Redmond, H Paul
    Affiliation
    Department of Academic Surgery, Cork University Hospital, Wilton, Cork, Ireland. , bjmanning2002@yahoo.com
    Issue Date
    2012-02-03T15:08:48Z
    MeSH
    Aged
    Aged, 80 and over
    Anti-Inflammatory Agents, Non-Steroidal/*adverse effects
    Aspirin/*adverse effects
    *Blood Loss, Surgical
    *Blood Transfusion
    Case-Control Studies
    Emergencies
    Female
    Femoral Neck Fractures/blood/*surgery
    Fracture Fixation/methods
    Hematocrit
    Hemoglobins/analysis
    Humans
    Male
    Preoperative Care/methods
    Prospective Studies
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    Citation
    Injury. 2004 Feb;35(2):121-4.
    Journal
    Injury
    URI
    http://hdl.handle.net/10147/208970
    PubMed ID
    14736467
    Abstract
    Although it is widely accepted that aspirin will increase the risk of intra- and post-operative bleeding, clinical studies have not consistently supported this assumption. We aimed to assess the effect of pre-operative aspirin on blood loss and transfusion requirements in patients undergoing emergency fixation of femoral neck fractures. A prospective case-control study was undertaken in patients presenting with femoral neck fractures. Parameters recorded included intra-operative blood loss, post-operative blood loss, transfusion requirements and peri-operative reduction in haemoglobin concentration. Of 89 patients presenting with femoral neck fractures 32 were on long-term aspirin therapy. Pre-operative aspirin ingestion did not significantly affect peri-operative blood loss, or change in haemoglobin concentration or haematocrit. However those patients taking aspirin pre-operatively had a significantly lower haemoglobin concentration and haematocrit and were more likely to be anaemic at presentation than those who were not receiving aspirin. Patients taking aspirin were also more likely to receive blood transfusion post-operatively.
    Language
    eng
    ISSN
    0020-1383 (Print)
    0020-1383 (Linking)
    Collections
    Cork University Hospital

    entitlement

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