The effect of aspirin on blood loss and transfusion requirements in patients with femoral neck fractures.
Authors
Manning, Brian JO'Brien, Noel
Aravindan, Selvaraj
Cahill, Ronan A
McGreal, Gerald
Redmond, H Paul
Affiliation
Department of Academic Surgery, Cork University Hospital, Wilton, Cork, Ireland. , bjmanning2002@yahoo.comIssue Date
2012-02-03T15:08:48ZMeSH
AgedAged, 80 and over
Anti-Inflammatory Agents, Non-Steroidal/*adverse effects
Aspirin/*adverse effects
*Blood Loss, Surgical
*Blood Transfusion
Case-Control Studies
Emergencies
Female
Femoral Neck Fractures/blood/*surgery
Fracture Fixation/methods
Hematocrit
Hemoglobins/analysis
Humans
Male
Preoperative Care/methods
Prospective Studies
Metadata
Show full item recordCitation
Injury. 2004 Feb;35(2):121-4.Journal
InjuryPubMed ID
14736467Abstract
Although it is widely accepted that aspirin will increase the risk of intra- and post-operative bleeding, clinical studies have not consistently supported this assumption. We aimed to assess the effect of pre-operative aspirin on blood loss and transfusion requirements in patients undergoing emergency fixation of femoral neck fractures. A prospective case-control study was undertaken in patients presenting with femoral neck fractures. Parameters recorded included intra-operative blood loss, post-operative blood loss, transfusion requirements and peri-operative reduction in haemoglobin concentration. Of 89 patients presenting with femoral neck fractures 32 were on long-term aspirin therapy. Pre-operative aspirin ingestion did not significantly affect peri-operative blood loss, or change in haemoglobin concentration or haematocrit. However those patients taking aspirin pre-operatively had a significantly lower haemoglobin concentration and haematocrit and were more likely to be anaemic at presentation than those who were not receiving aspirin. Patients taking aspirin were also more likely to receive blood transfusion post-operatively.Language
engISSN
0020-1383 (Print)0020-1383 (Linking)
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