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dc.contributor.authorCronin, E M P
dc.contributor.authorCoffey, J C
dc.contributor.authorHerlihy, D
dc.contributor.authorRomics, L
dc.contributor.authorAftab, F
dc.contributor.authorKeohane, C
dc.contributor.authorRedmond, H P
dc.date.accessioned2012-02-03T15:06:39Z
dc.date.available2012-02-03T15:06:39Z
dc.date.issued2012-02-03T15:06:39Z
dc.identifier.citationIr J Med Sci. 2005 Apr-Jun;174(2):63-6.en_GB
dc.identifier.issn0021-1265 (Print)en_GB
dc.identifier.issn0021-1265 (Linking)en_GB
dc.identifier.pmid16094917en_GB
dc.identifier.urihttp://hdl.handle.net/10147/208892
dc.description.abstractBACKGROUND: Ganglioneuroma is a rare tumour of neural crest origin, which arises from maturation of a neuroblastoma. While previously considered to be non-functioning, they are now known to be frequently endocrinologically active. AIMS AND METHODS: We report a case of a massive retroperitoneal ganglioneuroma presenting with small bowel obstruction in an adult, 18 years after initial diagnosis. Urinary dopamine levels were elevated, but other catecholamines were within normal limits. This is the first report in the English-language literature of a retroperitoneal ganglioneuroma presenting with or causing intestinal obstruction. We also review the metabolic, radiological, and histological features of these tumours. Relevant publications were identified from a Medline search using the MeSH headings 'ganglioneuroma', 'retroperitoneal neoplasms' and 'intestinal obstruction', and also from the reference lists of retrieved articles. CONCLUSIONS: Ganglioneuroma can grow to a massive size and present in a varied manner. It should be included in the differential diagnosis of any large retroperitoneal or mediastinal mass, including those causing bowel obstruction.
dc.language.isoengen_GB
dc.subject.meshAdulten_GB
dc.subject.meshDiagnosis, Differentialen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshGanglioneuroma/complications/*diagnosisen_GB
dc.subject.meshHumansen_GB
dc.subject.meshIntestinal Obstruction/*diagnosis/etiologyen_GB
dc.subject.meshIntestine, Small/*physiopathologyen_GB
dc.subject.meshRetroperitoneal Neoplasms/complications/*diagnosisen_GB
dc.subject.meshTime Factorsen_GB
dc.titleMassive retroperitoneal ganglioneuroma presenting with small bowel obstruction 18 years following initial diagnosis.en_GB
dc.contributor.departmentSurgical Professorial Unit, Department of Surgery, Cork University Hospital,, Wilton, Cork, Ireland.en_GB
dc.identifier.journalIrish journal of medical scienceen_GB
dc.description.provinceMunster
html.description.abstractBACKGROUND: Ganglioneuroma is a rare tumour of neural crest origin, which arises from maturation of a neuroblastoma. While previously considered to be non-functioning, they are now known to be frequently endocrinologically active. AIMS AND METHODS: We report a case of a massive retroperitoneal ganglioneuroma presenting with small bowel obstruction in an adult, 18 years after initial diagnosis. Urinary dopamine levels were elevated, but other catecholamines were within normal limits. This is the first report in the English-language literature of a retroperitoneal ganglioneuroma presenting with or causing intestinal obstruction. We also review the metabolic, radiological, and histological features of these tumours. Relevant publications were identified from a Medline search using the MeSH headings 'ganglioneuroma', 'retroperitoneal neoplasms' and 'intestinal obstruction', and also from the reference lists of retrieved articles. CONCLUSIONS: Ganglioneuroma can grow to a massive size and present in a varied manner. It should be included in the differential diagnosis of any large retroperitoneal or mediastinal mass, including those causing bowel obstruction.


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