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    The incidence of postoperative venous thrombosis among patients with ulcerative colitis.

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    Authors
    O'Connor, O J
    Cahill, R A
    Kirwan, W O
    Redmond, H P
    Affiliation
    Dept of Academic Surgery, Cork University Hospital, Wilton, Cork.
    Issue Date
    2012-02-03T15:06:22Z
    MeSH
    Adolescent
    Adult
    Aged
    Child
    Child, Preschool
    Colitis, Ulcerative/complications/*surgery
    Female
    Humans
    Incidence
    Ireland
    Male
    Middle Aged
    Postoperative Complications/*epidemiology
    Risk Assessment
    Risk Factors
    Venous Thrombosis/epidemiology/*etiology
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    Citation
    Ir J Med Sci. 2005 Jul-Sep;174(3):20-2.
    Journal
    Irish journal of medical science
    URI
    http://hdl.handle.net/10147/208882
    PubMed ID
    16285333
    Abstract
    BACKGROUND: Patients with Ulcerative Colitis (UC) have inherent prothrombotic tendencies. It is unknown whether this necessitates the use of additional perioperative anti-thrombotic prophylaxis when such patients require major surgery. METHODS: The postoperative courses of 79 patients with UC undergoing 180 major abdominal and pelvic operations were examined for clinical and radiological evidence of venous thrombosis. Eighteen patients with Familial Adenomatous Polyposis (FAP) having surgery (35 operations) of similar magnitude were also studied. Standard anti-thrombosis prophylaxis was utilised in all patients. RESULTS: Nine patients with UC were clinically suspected of developing postoperative venous thrombosis, but only three (3.8%) had their diagnosis confirmed radiologically (all had a pulmonary embolus). Therefore, the overall postoperative thrombosis rate, on an intention to treat basis, was 1.7% (3/180). No patient with FAP developed significant venous thrombosis. CONCLUSION: Standard perioperative antithrombotic modalities are sufficient to maintain any potential increase in postoperative thrombotic risk at an acceptable level in patients with UC undergoing operative intervention.
    Language
    eng
    ISSN
    0021-1265 (Print)
    0021-1265 (Linking)
    Collections
    Cork University Hospital

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