• Login
    View Item 
    •   Home
    • Hospital Research
    • Munster
    • Cork University Hospital
    • View Item
    •   Home
    • Hospital Research
    • Munster
    • Cork University Hospital
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Map of Submissions

    Home Page
    UlsterN
    4378
    UlsterS
    4378
    Connacht
    1408
    Munster
    62
    Leinster
    426

    Browse

    All of Lenus, The Irish Health RepositoryCommunitiesTitleAuthorsDate publishedSubjectsThis CollectionTitleAuthorsDate publishedSubjects

    My Account

    LoginRegister

    About

    About LenusDirectory of Open Access JournalsOpen Access Publishing GuideHSE Library Guide to Publishers' PoliciesFAQsTerms and ConditionsVision StatementORCID Unique identifiers for ResearchersHSE position statement on Open AccessNational Open Research Forum (NORF)Zenodo (European Open Research repository)

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Sentinel lymph node biopsy: is it possible to reduce false negative rates by excluding patients with nodular melanoma?

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Authors
    Corrigan, M A
    Coffey, J C
    O'Sullivan, M J
    Fogarty, K M
    Redmond, H P
    Affiliation
    Department of Academic Surgery, Cork University Hospital, Ireland., mark@surgent.ie
    Issue Date
    2012-02-03T15:05:03Z
    MeSH
    Adolescent
    Adult
    Aged
    Aged, 80 and over
    Cohort Studies
    False Negative Reactions
    Female
    Humans
    Lymphatic Metastasis
    Male
    Melanoma/*secondary
    Middle Aged
    Neoplasm Recurrence, Local/*pathology
    *Sentinel Lymph Node Biopsy
    Skin Neoplasms/*pathology
    Show allShow less
    
    Metadata
    Show full item record
    Citation
    Surgeon. 2006 Jun;4(3):153-7.
    Journal
    The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
    URI
    http://hdl.handle.net/10147/208839
    PubMed ID
    16764200
    Abstract
    OBJECTIVE: The aim of this study was to review the outcome of sentinel lymph node biopsy (SLNB) in patients with melanoma and to delineate whether patients with nodular melanoma are more likely to develop nodal recurrence despite negative SLNB. METHODS: Consecutive patients with cutaneous melanoma undergoing SLNB were identified from a departmental database between 1997 and 2005. Factors including demographic data, site, histological subtype, depth and outcome were examined. RESULTS: Of 131 patients, 103 were node negative and eligible for study. The median age was 53 (16-82) years with 46 patients being male (45%) and 57 female (55%). Primary melanoma sites included lower limb (49; 48%), upper limb (29; 28%), head (12; 11%), trunk (7; 7%) and back (6; 6%). The median Breslow thickness was 2mm. Superficial spreading accounted for 43% of melanoma with nodular accounting for 42%. Median follow-up was 40 (3-90) months. Of 20 relapses, seven recurred in the same nodal basin, three were satellite recurrences, one recurred with both satellite and nodal lesions simultaneously, and nine experienced haematogenous spread. Of the eight patients who developed recurrence in the same nodal basin, four were of nodular histological subtype (p=NS). All of the three patients with satellite lesions had nodular melanoma histologically (p=0.02). When nodal and satellite recurrences were combined, eight of 11 were histologically nodular (p=0.01). CONCLUSIONS: This study indicates that lymphatic recurrence occurs more often in SLNB negative patients with nodular melanoma. Further evaluation of the inclusion criteria for sentinel node biopsy is warranted.
    Language
    eng
    ISSN
    1479-666X (Print)
    1479-666X (Linking)
    Collections
    Cork University Hospital

    entitlement

    Related articles

    • Cervical sentinel lymph node biopsy for melanomas of the head and neck and upper thorax.
    • Authors: Wagner JD, Park HM, Coleman JJ 3rd, Love C, Hayes JT
    • Issue date: 2000 Mar
    • Nodular Histologic Subtype and Ulceration are Tumor Factors Associated with High Risk of Recurrence in Sentinel Node-Negative Melanoma Patients.
    • Authors: Faut M, Wevers KP, van Ginkel RJ, Diercks GF, Hoekstra HJ, Kruijff S, Been LB, van Leeuwen BL
    • Issue date: 2017 Jan
    • Sentinel lymph node biopsy is indicated for patients with thick clinically lymph node-negative melanoma.
    • Authors: Yamamoto M, Fisher KJ, Wong JY, Koscso JM, Konstantinovic MA, Govsyeyev N, Messina JL, Sarnaik AA, Cruse CW, Gonzalez RJ, Sondak VK, Zager JS
    • Issue date: 2015 May 15
    • Sentinel Lymph Node Biopsy for Cutaneous Head and Neck Melanoma: Mapping the Parotid Gland.
    • Authors: Picon AI, Coit DG, Shaha AR, Brady MS, Boyle JO, Singh BB, Wong RJ, Busam KJ, Shah JP, Kraus DH
    • Issue date: 2016 Dec
    • Patterns of initial recurrence and prognosis after sentinel lymph node biopsy and selective lymphadenectomy for melanoma.
    • Authors: Wagner JD, Ranieri J, Evdokimow DZ, Logan T, Chuang TY, Johnson CS, Jung SH, Wenck S, Coleman JJ 3rd
    • Issue date: 2003 Aug
    HSE Library | Health Service Executive | Dr Steevens’ Hospital, Dublin 8 | Republic of Ireland | Eircode: D08 W2A8
    lenus@hse.ie
    DSpace software copyright © 2002-2017  DuraSpace
    Contact Us | Disclaimer
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.