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    Management of chronic constipation in the elderly.

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    Authors
    Gallagher, Paul F
    O'Mahony, Denis
    Quigley, Eamonn M M
    Affiliation
    Department of Geriatric Medicine, Cork University Hospital, Alimentary, Pharmabiotic Centre, University College Cork, Cork, Ireland.
    Issue Date
    2012-02-03T15:04:20Z
    MeSH
    Aged
    Chronic Disease
    Constipation/complications/physiopathology/*therapy
    Fecal Impaction/complications/therapy
    *Health Services for the Aged
    Humans
    Laxatives/therapeutic use
    Life Style
    Suppositories/therapeutic use
    
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    Citation
    Drugs Aging. 2008;25(10):807-21.
    Journal
    Drugs & aging
    URI
    http://hdl.handle.net/10147/208818
    PubMed ID
    18808206
    Abstract
    Constipation is a significant healthcare problem in the elderly. However, while undoubtedly common in the elderly, data on the prevalence of constipation in general and of its subtypes vary considerably, depending on the nature of the study population and their location. Furthermore, the complexity of the pathophysiology of constipation in this age group is little appreciated. Assumptions regarding 'age-related changes in colorectal physiology' are, for the most part, not supported by scientific evidence and may serve to distract the clinician from uncovering the contributions of co-morbid diseases and the impact of iatrogenic factors. The evidence base from which one can develop recommendations on the management of constipation in the elderly is, for the most part, slim. This becomes most starkly apparent when one attempts to critically assess specific approaches to management. There is insufficient evidence to support the use of many commonly used laxatives both in the general population and in the elderly. Lifestyle interventions have value for some patients but data are lacking on the benefits of these interventions for patients with chronic constipation. Data in the elderly do not exist for most new pharmacological approaches to constipation. Pending the availability of good data, management of constipation in the elderly should be tailored to each individual's needs and expectations, regardless of age or place of residence. In certain situations, constipation may be complicated by the development of impaction; preventive strategies are important in this context. We urge enrolment of many more elderly individuals with chronic constipation in clinical trials designed to address their particular needs.
    Language
    eng
    ISSN
    1170-229X (Print)
    1170-229X (Linking)
    Collections
    Cork University Hospital

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