Sweeten, soother and swaddle for retinopathy of prematurity screening: a randomised placebo controlled trial.
Affiliation
Department of Paediatrics and Newborn Medicine, Coombe Women and Infants, University Hospital, Dublin, Ireland.Issue Date
2012-02-01T10:56:57ZMeSH
Administration, OralAnalgesia/*methods
Analgesics/administration & dosage
Female
Humans
Infant Care/methods
Infant, Newborn
Infant, Premature
Intensive Care, Neonatal/methods
Male
Neonatal Screening/*adverse effects/methods
*Pacifiers
Pain/etiology/*prevention & control
Pain Measurement/methods
Physical Examination/adverse effects/methods
Prospective Studies
Retinopathy of Prematurity/*diagnosis
Sucrose/administration & dosage
Metadata
Show full item recordCitation
Arch Dis Child Fetal Neonatal Ed. 2010 Nov;95(6):F419-22. Epub 2010 Sep 28.Journal
Archives of disease in childhood. Fetal and neonatal editionDOI
10.1136/adc.2009.180943PubMed ID
20876596Abstract
OBJECTIVE: To assess the efficacy of oral sucrose combined with swaddling and non-nutritive suck (NNS) as a method for reducing pain associated with retinopathy of prematurity (ROP) screening. DESIGN: Randomised placebo controlled study. SETTING: Tertiary level neonatal intensive care unit. SAMPLE: 40 infants undergoing primary eye examination for ROP screening. INTERVENTION: The control group were swaddled, and received 0.2 ml of sterile water given by mouth using a syringe and a soother. The intervention group were swaddled, and received 0.2 ml of sucrose 24% given by mouth using a syringe and a soother. RESULTS: 40 infants were included in the study. There was no difference in mean gestational age at birth, mean birth weight or corrected gestational age at first examination between both groups. The sucrose group had a significantly lower median Neonatal Pain, Agitation and Sedation Scale (N-PASS) score during ROP screening, initially following insertion of the speculum (6.5 vs 5, p=0.02) and subsequently during scleral indentation (9.5 vs 7.5, p=0.03). Fewer infants experienced episodes of desaturations or bradycardia in the intervention group (1 vs 4, p=0.18). CONCLUSION: ROP screening is a necessary but recognised painful procedure. Sucrose combined with NNS and swaddling reduced the behavioural and physiological pain responses. However, pain scores remained consistently high and appropriate pain relief for ROP screening remains a challenge.Language
engISSN
1468-2052 (Electronic)1359-2998 (Linking)
ae974a485f413a2113503eed53cd6c53
10.1136/adc.2009.180943