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    Ectopic pituitary adenoma presenting as midline nasopharyngeal mass.

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    Authors
    Ali, R
    Noma, U
    Jansen, M
    Smyth, D
    Affiliation
    Department of Otolaryngology, Waterford Regional Hospital, Dunmore Road,, Waterford, Ireland. rohana.oconnell@gmail.com
    Issue Date
    2012-02-01T10:52:45Z
    MeSH
    Adenoma/metabolism/*pathology
    Craniopharyngioma/*pathology
    Female
    Humans
    Immunohistochemistry
    Magnetic Resonance Imaging
    Middle Aged
    Nasopharyngeal Neoplasms/metabolism/*pathology
    Pituitary Neoplasms/pathology
    
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    Citation
    Ir J Med Sci. 2010 Dec;179(4):593-5. Epub 2009 Jan 8.
    Journal
    Irish journal of medical science
    URI
    http://hdl.handle.net/10147/207964
    DOI
    10.1007/s11845-008-0236-x
    PubMed ID
    19129981
    Abstract
    INTRODUCTION: Ectopic pituitary adenomas are extremely rare. We report a case of ectopic pituitary adenoma in the midline of the nasopharynx. This adenoma probably arose from the pharyngeal remnant of Rathke's pouch. METHODS: We discuss a case of a lady who presented to our unit with 2 months history of dryness and sensation of lump in her throat and a long standing history of hypothyroidism. Examination of nasopharynx revealed a smooth and fluctuant midline mass. CT scan of nose and paranasal sinuses confirmed the midline mass with small defect communicating with the sphenoid sinus. An initial diagnosis of Thornwaldt's cyst was made and she underwent upper aerodigestive tract endoscopy and marsupialization of the mass. Histopathological examination revealed ectopic pituitary adenoma. CONCLUSION: Ectopic pituitary adenoma is an important differential diagnosis for a midline nasopharyngeal mass. It is recommended that prior to surgical resection of midline nasopharyngeal mass biopsy is taken and MRI is performed.
    Language
    eng
    ISSN
    1863-4362 (Electronic)
    0021-1265 (Linking)
    ae974a485f413a2113503eed53cd6c53
    10.1007/s11845-008-0236-x
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    University Hospital Waterford

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