Ectopic pituitary adenoma presenting as midline nasopharyngeal mass.
Affiliation
Department of Otolaryngology, Waterford Regional Hospital, Dunmore Road,, Waterford, Ireland. rohana.oconnell@gmail.comIssue Date
2012-02-01T10:52:45ZMeSH
Adenoma/metabolism/*pathologyCraniopharyngioma/*pathology
Female
Humans
Immunohistochemistry
Magnetic Resonance Imaging
Middle Aged
Nasopharyngeal Neoplasms/metabolism/*pathology
Pituitary Neoplasms/pathology
Metadata
Show full item recordCitation
Ir J Med Sci. 2010 Dec;179(4):593-5. Epub 2009 Jan 8.Journal
Irish journal of medical scienceDOI
10.1007/s11845-008-0236-xPubMed ID
19129981Abstract
INTRODUCTION: Ectopic pituitary adenomas are extremely rare. We report a case of ectopic pituitary adenoma in the midline of the nasopharynx. This adenoma probably arose from the pharyngeal remnant of Rathke's pouch. METHODS: We discuss a case of a lady who presented to our unit with 2 months history of dryness and sensation of lump in her throat and a long standing history of hypothyroidism. Examination of nasopharynx revealed a smooth and fluctuant midline mass. CT scan of nose and paranasal sinuses confirmed the midline mass with small defect communicating with the sphenoid sinus. An initial diagnosis of Thornwaldt's cyst was made and she underwent upper aerodigestive tract endoscopy and marsupialization of the mass. Histopathological examination revealed ectopic pituitary adenoma. CONCLUSION: Ectopic pituitary adenoma is an important differential diagnosis for a midline nasopharyngeal mass. It is recommended that prior to surgical resection of midline nasopharyngeal mass biopsy is taken and MRI is performed.Language
engISSN
1863-4362 (Electronic)0021-1265 (Linking)
ae974a485f413a2113503eed53cd6c53
10.1007/s11845-008-0236-x