Do we really understand the role of the oesophagogastric junction in disease?
AffiliationDepartment of Medical Physics and Clinical Engineering, Adelaide and Meath, Hospital, Tallaght, Dublin 24, Ireland. email@example.com
MeSHDiagnostic Techniques, Digestive System
MetadataShow full item record
CitationWorld J Gastroenterol. 2009 Jan 14;15(2):144-50.
JournalWorld journal of gastroenterology : WJG
AbstractThe role of the oesophago-gastric junction (OGJ) in gastro-oesophageal reflux disease is still not completely understood, and there is no clinically used method to assess the OGJ function in patients. Only indirect methods such as pH studies are carried out. The OGJ acts a valve controlling the flow of solids, liquids and gases between the oesophagus and the stomach. Manometry can determine if a sphincter is toned or relaxed; but, it cannot confirm that the sphincter region is actually open. Distension is a new technique for measuring function in the OGJ. By measuring the cross-sectional area through the narrow region in the junction during distension of a catheter mounted bag, much more information on the opening and closing patterns of the junction can be determined. This technique has already been demonstrated to show changes in the OGJ after surgical treatments for reflux disease. New measurement ideas around the concept of distending the OGJ offer new hope that a clinically useable test for compliance at the junction can be developed and could potentially help in determining appropriate therapy.
- Functional oesophago-gastric junction imaging.
- Authors: McMahon BP, Drewes AM, Gregersen H
- Issue date: 2006 May 14
- [The value of twenty-four hour intraoesophageal pH monitoring and manometry in the management of patients with upper gastrointestinal symptoms].
- Authors: Lakner L, Döbrönte Z
- Issue date: 2009 Oct 25
- Prolonged measurement of lower oesophageal sphincter function in patients with intestinal metaplasia at the oesophagogastric junction.
- Authors: Wolf C, Timmer R, Breumelhof R, Seldenrijk CA, Smout AJ
- Issue date: 2001 Sep
- Computation of flow through the oesophagogastric junction.
- Authors: McMahon BP, Odie KD, Moloney KW, Gregersen H
- Issue date: 2007 Mar 7
- Measuring mechanical properties of the esophageal wall using impedance planimetry.
- Authors: Moonen A, Boeckxstaens G
- Issue date: 2014 Oct