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    Efficacy of triamcinolone acetonide and bupivacaine for pain after lumbar discectomy.

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    Authors
    Bahari, Syah
    El-Dahab, Mohamed
    Cleary, May
    Sparkes, Joseph
    Affiliation
    Department of Trauma and Reconstructive Surgery, Adelaide and Meath Hospital, incorporating the National Children Hospital, Tallaght, Dublin 24, Republic of, Ireland. syahbahari@gmail.com
    Issue Date
    2012-02-01T10:49:37Z
    MeSH
    Analgesia/methods
    Anesthetics, Local/therapeutic use
    Anti-Inflammatory Agents/therapeutic use
    Bupivacaine/*therapeutic use
    *Diskectomy
    Drug Therapy, Combination
    Female
    Humans
    Lumbar Vertebrae/*surgery
    Male
    Pain Measurement/*drug effects
    Pain, Postoperative/*drug therapy
    Prospective Studies
    Statistics, Nonparametric
    Treatment Outcome
    Triamcinolone Acetonide/*therapeutic use
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    Citation
    Eur Spine J. 2010 Jul;19(7):1099-103. Epub 2010 Mar 12.
    Journal
    European spine journal : official publication of the European Spine Society, the , European Spinal Deformity Society, and the European Section of the Cervical Spine, Research Society
    URI
    http://hdl.handle.net/10147/207903
    DOI
    10.1007/s00586-010-1360-7
    PubMed ID
    20224868
    Abstract
    The study is a prospective blinded randomised controlled trial to compare the efficacy of triamcinolone acetonide, bupivacaine or in combination in managing pain after lumbar discectomy. Patients undergoing primary single-level lumbar discectomy were randomised. Triamcinolone acetonide, bupivacaine or in combination was instilled at the nerve root as decompression. Preoperative, day 1 and 6 weeks pain score, 24-h postoperative opiate requirements and duration of inpatient stay were recorded. Data was analysed using Mann-Whitney test for statistical significance. 100 patients were recruited. A significant difference was noted in day one postoperative mean pain score, mean 24-h opiate requirement and mean inpatient stay in the triamcinolone acetonide and bupivacaine group. At 8 weeks postoperatively, no significant differences were seen in the pain score in all groups. Significant postoperative pain reduction and opiate requirements in the first 24 h, and significantly shortened duration of inpatient stay were achieved in the triamcinolone acetonide and bupivacaine group compared with other groups.
    Language
    eng
    ISSN
    1432-0932 (Electronic)
    0940-6719 (Linking)
    ae974a485f413a2113503eed53cd6c53
    10.1007/s00586-010-1360-7
    Scopus Count
    Collections
    Tallaght University Hospital

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