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    Treatment of Helicobacter pylori infection 2011.

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    Authors
    O'Connor, Anthony
    Gisbert, Javier P
    McNamara, Deirdre
    O'Morain, Colm
    Affiliation
    Department of Gastroenterology, Adelaide and Meath Hospital incorporating the, National Children's Hospital/Trinity College Dublin, Dublin, Ireland., jpoconno@tcd.ie
    Issue Date
    2012-02-01T10:49:10Z
    MeSH
    Anti-Bacterial Agents/*therapeutic use
    Clinical Trials as Topic
    Drug Therapy, Combination
    Helicobacter Infections/*drug therapy/genetics/microbiology
    Helicobacter pylori/*drug effects
    Humans
    Probiotics/*therapeutic use
    Proton Pump Inhibitors/*therapeutic use
    
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    Citation
    Helicobacter. 2011 Sep;16 Suppl 1:53-8. doi: 10.1111/j.1523-5378.2011.00881.x.
    Journal
    Helicobacter
    URI
    http://hdl.handle.net/10147/207887
    DOI
    10.1111/j.1523-5378.2011.00881.x
    PubMed ID
    21896086
    Abstract
    This article reviews the literature published pertaining to Helicobacter pylori eradication over the last year. The general perception among clinicians and academics engaged in research on H. pylori has been that eradication rates for first-line therapies are falling, although some data published this year have cast doubt on this. The studies published this year have therefore focussed on developing alternative strategies for the first-line eradication of H. pylori. In this regard, clear evidence now exists that both levofloxacin and bismuth are viable options for first-line therapy. The sequential and "concomitant" regimes have also been studied in new settings and may have a role in future algorithms also. In addition, data have emerged that the probiotic Saccharomyces boulardii may be a useful adjunct to antibiotic therapy. Other studies promote individualized therapies based on host polymorphisms, age, and other such demographic factors.
    Language
    eng
    ISSN
    1523-5378 (Electronic)
    1083-4389 (Linking)
    ae974a485f413a2113503eed53cd6c53
    10.1111/j.1523-5378.2011.00881.x
    Scopus Count
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    Tallaght University Hospital

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