Infliximab-associated alveolitis after treatment for severe left-sided ulcerative colitis.
Affiliation
Department of Gastroenterology, Adelaide and Meath Hospital, Tallaght, Dublin,, Republic of Ireland. sveerappan@rcsi.ieIssue Date
2012-02-01T10:48:20ZMeSH
AgedAntibodies, Monoclonal/*adverse effects
Colitis, Ulcerative/*drug therapy/pathology
Gastrointestinal Agents/*adverse effects
Humans
Male
Pulmonary Fibrosis/*chemically induced
Treatment Outcome
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Eur J Gastroenterol Hepatol. 2009 Jul;21(7):830-2.Journal
European journal of gastroenterology & hepatologyDOI
10.1097/MEG.0b013e32830fb700PubMed ID
19398919Abstract
Here we describe a patient with ulcerative colitis who developed alveolitis after infliximab therapy. With earlier case reports of development of alveolitis in rheumatoid arthritis patients after infliximab infusion, the temporal relationship between the infliximab therapy and the development of alveolitis in this case, raises the possibility that the two might be causally related. With an increasing trend towards treating moderate to severely active ulcerative colitis patients with infliximab as a rescue therapy, clinicians should be aware of this potentially serious complication.Language
engISSN
1473-5687 (Electronic)0954-691X (Linking)
ae974a485f413a2113503eed53cd6c53
10.1097/MEG.0b013e32830fb700
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