Complete clinical response to neoadjuvant chemotherapy in a 54-year-old male with Askin tumor.
AffiliationDepartment of Surgery, Adelaide and Meath Hospital, Tallaght, Dublin, Ireland., firstname.lastname@example.org
MeSHAntineoplastic Combined Chemotherapy Protocols/*therapeutic use
Neuroectodermal Tumors, Primitive/*drug therapy/pathology/surgery
Thoracic Neoplasms/*drug therapy/pathology/surgery
Tomography, X-Ray Computed
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CitationThorac Cardiovasc Surg. 2010 Aug;58(5):306-8. Epub 2010 Aug 2.
JournalThe Thoracic and cardiovascular surgeon
AbstractAskin tumor is a tumor of the thoracopulmonary region that most commonly affects children and adolescents. These rare tumors are a form of primitive neuroectodermal tumor and typically carry a poor prognosis. Treatment is multimodal and consists of a combination of neoadjuvant chemotherapy, radical resection, and adjuvant chemo- and radiotherapy or all of the above. Surgery is advocated in most cases. We report a case of Askin tumor in a 54-year-old male who showed rapid and complete response to neoadjuvant chemotherapy. This allowed potentially radical surgery to be avoided. At one-year follow-up he remains disease-free.