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dc.contributor.authorO'Neill, J P
dc.contributor.authorMoynagh, M
dc.contributor.authorKavanagh, E
dc.contributor.authorO'Dwyer, T
dc.date.accessioned2012-02-01T11:08:56Z
dc.date.available2012-02-01T11:08:56Z
dc.date.issued2012-02-01T11:08:56Z
dc.identifier.citationJ Laryngol Otol. 2010 Dec;124(12):1274-7. Epub 2010 Jun 11.en_GB
dc.identifier.issn1748-5460 (Electronic)en_GB
dc.identifier.issn0022-2151 (Linking)en_GB
dc.identifier.pmid20537210en_GB
dc.identifier.doi10.1017/S0022215110001398en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207845
dc.description.abstractOBJECTIVES: To compare the use of computed tomography - positron emission tomography and whole-body magnetic resonance imaging for the staging of head and neck cancer. PATIENTS AND METHODS: From January to July 2009, 15 consecutive head and neck cancer patients (11 men and four women; mean age 59 years; age range 19 to 81 years) underwent computed tomography - positron emission tomography and whole-body magnetic resonance imaging for pre-therapeutic evaluation. All scans were staged, as per the American Joint Committee on Cancer tumour-node-metastasis classification, by two blinded consultant radiologists, in two sittings. Diagnoses were confirmed by histopathological examination of endoscopic biopsies, and in some cases whole surgical specimens. RESULTS: Tumour staging showed a 74 per cent concordance, node staging an 80 per cent concordance and metastasis staging a 100 per cent concordance, comparing the two imaging modalities. CONCLUSION: This study found radiological staging discordance between the two imaging modalities. Whole-body magnetic resonance imaging is an emerging staging modality with superior visualisation of metastatic disease, which does not require exposure to ionising radiation.
dc.language.isoengen_GB
dc.subject.meshAdulten_GB
dc.subject.meshAgeden_GB
dc.subject.meshAged, 80 and overen_GB
dc.subject.meshBiopsyen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshFluorodeoxyglucose F18/diagnostic useen_GB
dc.subject.meshHead and Neck Neoplasms/*diagnosis/pathology/radionuclide imagingen_GB
dc.subject.meshHumansen_GB
dc.subject.meshMagnetic Resonance Imaging/*methodsen_GB
dc.subject.meshMaleen_GB
dc.subject.meshMiddle Ageden_GB
dc.subject.meshNeoplasm Recurrence, Local/diagnosis/radionuclide imagingen_GB
dc.subject.meshNeoplasm Stagingen_GB
dc.subject.mesh*Positron-Emission Tomographyen_GB
dc.subject.meshPredictive Value of Testsen_GB
dc.subject.meshProspective Studiesen_GB
dc.subject.meshRadiopharmaceuticals/diagnostic useen_GB
dc.subject.meshWhole Body Imaging/*methodsen_GB
dc.subject.meshYoung Adulten_GB
dc.titleProspective, blinded trial of whole-body magnetic resonance imaging versus computed tomography positron emission tomography in staging primary and recurrent cancer of the head and neck.en_GB
dc.contributor.departmentDepartment of Otolaryngology, Head and Neck Surgery, The Mater Hospital, Dublin, , Ireland. joneill@rcsi.ieen_GB
dc.identifier.journalThe Journal of laryngology and otologyen_GB
dc.description.provinceLeinster
html.description.abstractOBJECTIVES: To compare the use of computed tomography - positron emission tomography and whole-body magnetic resonance imaging for the staging of head and neck cancer. PATIENTS AND METHODS: From January to July 2009, 15 consecutive head and neck cancer patients (11 men and four women; mean age 59 years; age range 19 to 81 years) underwent computed tomography - positron emission tomography and whole-body magnetic resonance imaging for pre-therapeutic evaluation. All scans were staged, as per the American Joint Committee on Cancer tumour-node-metastasis classification, by two blinded consultant radiologists, in two sittings. Diagnoses were confirmed by histopathological examination of endoscopic biopsies, and in some cases whole surgical specimens. RESULTS: Tumour staging showed a 74 per cent concordance, node staging an 80 per cent concordance and metastasis staging a 100 per cent concordance, comparing the two imaging modalities. CONCLUSION: This study found radiological staging discordance between the two imaging modalities. Whole-body magnetic resonance imaging is an emerging staging modality with superior visualisation of metastatic disease, which does not require exposure to ionising radiation.


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