Prospective, blinded trial of whole-body magnetic resonance imaging versus computed tomography positron emission tomography in staging primary and recurrent cancer of the head and neck.
AffiliationDepartment of Otolaryngology, Head and Neck Surgery, The Mater Hospital, Dublin, , Ireland. email@example.com
Aged, 80 and over
Fluorodeoxyglucose F18/diagnostic use
Head and Neck Neoplasms/*diagnosis/pathology/radionuclide imaging
Magnetic Resonance Imaging/*methods
Neoplasm Recurrence, Local/diagnosis/radionuclide imaging
Predictive Value of Tests
Whole Body Imaging/*methods
MetadataShow full item record
CitationJ Laryngol Otol. 2010 Dec;124(12):1274-7. Epub 2010 Jun 11.
JournalThe Journal of laryngology and otology
AbstractOBJECTIVES: To compare the use of computed tomography - positron emission tomography and whole-body magnetic resonance imaging for the staging of head and neck cancer. PATIENTS AND METHODS: From January to July 2009, 15 consecutive head and neck cancer patients (11 men and four women; mean age 59 years; age range 19 to 81 years) underwent computed tomography - positron emission tomography and whole-body magnetic resonance imaging for pre-therapeutic evaluation. All scans were staged, as per the American Joint Committee on Cancer tumour-node-metastasis classification, by two blinded consultant radiologists, in two sittings. Diagnoses were confirmed by histopathological examination of endoscopic biopsies, and in some cases whole surgical specimens. RESULTS: Tumour staging showed a 74 per cent concordance, node staging an 80 per cent concordance and metastasis staging a 100 per cent concordance, comparing the two imaging modalities. CONCLUSION: This study found radiological staging discordance between the two imaging modalities. Whole-body magnetic resonance imaging is an emerging staging modality with superior visualisation of metastatic disease, which does not require exposure to ionising radiation.