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    Prospective, blinded trial of whole-body magnetic resonance imaging versus computed tomography positron emission tomography in staging primary and recurrent cancer of the head and neck.

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    Authors
    O'Neill, J P
    Moynagh, M
    Kavanagh, E
    O'Dwyer, T
    Affiliation
    Department of Otolaryngology, Head and Neck Surgery, The Mater Hospital, Dublin, , Ireland. joneill@rcsi.ie
    Issue Date
    2012-02-01T11:08:56Z
    MeSH
    Adult
    Aged
    Aged, 80 and over
    Biopsy
    Female
    Fluorodeoxyglucose F18/diagnostic use
    Head and Neck Neoplasms/*diagnosis/pathology/radionuclide imaging
    Humans
    Magnetic Resonance Imaging/*methods
    Male
    Middle Aged
    Neoplasm Recurrence, Local/diagnosis/radionuclide imaging
    Neoplasm Staging
    *Positron-Emission Tomography
    Predictive Value of Tests
    Prospective Studies
    Radiopharmaceuticals/diagnostic use
    Whole Body Imaging/*methods
    Young Adult
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    Citation
    J Laryngol Otol. 2010 Dec;124(12):1274-7. Epub 2010 Jun 11.
    Journal
    The Journal of laryngology and otology
    URI
    http://hdl.handle.net/10147/207845
    DOI
    10.1017/S0022215110001398
    PubMed ID
    20537210
    Abstract
    OBJECTIVES: To compare the use of computed tomography - positron emission tomography and whole-body magnetic resonance imaging for the staging of head and neck cancer. PATIENTS AND METHODS: From January to July 2009, 15 consecutive head and neck cancer patients (11 men and four women; mean age 59 years; age range 19 to 81 years) underwent computed tomography - positron emission tomography and whole-body magnetic resonance imaging for pre-therapeutic evaluation. All scans were staged, as per the American Joint Committee on Cancer tumour-node-metastasis classification, by two blinded consultant radiologists, in two sittings. Diagnoses were confirmed by histopathological examination of endoscopic biopsies, and in some cases whole surgical specimens. RESULTS: Tumour staging showed a 74 per cent concordance, node staging an 80 per cent concordance and metastasis staging a 100 per cent concordance, comparing the two imaging modalities. CONCLUSION: This study found radiological staging discordance between the two imaging modalities. Whole-body magnetic resonance imaging is an emerging staging modality with superior visualisation of metastatic disease, which does not require exposure to ionising radiation.
    Language
    eng
    ISSN
    1748-5460 (Electronic)
    0022-2151 (Linking)
    ae974a485f413a2113503eed53cd6c53
    10.1017/S0022215110001398
    Scopus Count
    Collections
    Mater Misericordiae Hospital

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