The impact of a revised EQ-5D population scoring on preference-based utility scores in an inflammatory arthritis cohort.
Craig, Benjamin M
Walsh, Cathal D
Veale, Douglas J
AffiliationNational Centre for Pharmacoeconomics, St. James Hospital, Dublin, Ireland., email@example.com
Aged, 80 and over
Quality of Life
MetadataShow full item record
CitationValue Health. 2011 Sep-Oct;14(6):921-7. Epub 2011 Jul 8.
JournalValue in health : the journal of the International Society for Pharmacoeconomics , and Outcomes Research
AbstractBACKGROUND AND OBJECTIVE: It is well established that there are problems with the EQ-5D. This is due to the original scoring methods used and how negative time trade-off (TTO) values were treated. A revised scoring method has been published. This article applies this to an inflammatory arthritis cohort. The objective is to examine the impact of a revised scoring system for the EQ-5D (UK) TTO on the utility estimates and in the case of rheumatoid arthritis, to explore the impact of using different utility metrics on the incremental cost-effectiveness ratio (ICER) results of an economic model. METHODS: A total of 504 patients with inflammatory arthritis were rescored using revised EQ-5D scoring, which uses an episodic random utility model to deal with negative TTO values. Differences in utility scores were compared and the new mapping coefficients were obtained. These were then used in an economic model to examine the impact on the ICER. RESULTS: In rheumatoid arthritis, the overall change is less for the revised EQ-5D scoring than with the original EQ-5D (TTO) but greater than the SF-6D: EQ-5D UK -0.22 (95% confidence interval [CI] -0.30 to -0.15), revised EQ-5D UK -0.16 (95% CI -0.21 to -0.10) and SF-6D -0.08 (95% CI -0.11 to -0.05). A similar trend is seen in the psoriatic arthritis group. The economic model produced different ICERs, when different utility measures were used; EQ-5D (TTO) euro42,402, SF-6D euro111,788, and revised EQ-5D (TTO) euro57,747. CONCLUSION: In the context of inflammatory arthritis, this article demonstrates that a revised scoring for EQ-5D may have a significant impact on utility estimates and on the output of the economic model.
- Understanding the relationship between the EQ-5D, SF-6D, HAQ and disease activity in inflammatory arthritis.
- Authors: Adams R, Walsh C, Veale D, Bresnihan B, FitzGerald O, Barry M
- Issue date: 2010
- A comparison of utility measurement using EQ-5D and SF-6D preference-based generic instruments in patients with rheumatoid arthritis.
- Authors: Salaffi F, Carotti M, Ciapetti A, Gasparini S, Grassi W
- Issue date: 2011 Jul-Aug
- Assessing utility values in rheumatoid arthritis: a comparison between time trade-off and the EuroQol.
- Authors: Ariza-Ariza R, Hernández-Cruz B, Carmona L, Dolores Ruiz-Montesinos M, Ballina J, Navarro-Sarabia F, Costs and Quality of Life in Rheumatoid Arthritis Study Group.
- Issue date: 2006 Oct 15
- Comparison of EuroQol-5D and short form-6D utility scores in multiethnic Asian patients with psoriatic arthritis: a cross-sectional study.
- Authors: Leung YY, Png ME, Wee HL, Thumboo J
- Issue date: 2013 Jun
- Exploring the validity of estimating EQ-5D and SF-6D utility values from the health assessment questionnaire in patients with inflammatory arthritis.
- Authors: Harrison MJ, Lunt M, Verstappen SM, Watson KD, Bansback NJ, Symmons DP
- Issue date: 2010 Feb 11