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    Self-administered outpatient parenteral antimicrobial therapy: a report of three years experience in the Irish healthcare setting.

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    Authors
    Kieran, J
    O'Reilly, A
    Parker, J
    Clarke, S
    Bergin, C
    Affiliation
    Department of Genitourinary Medicine and Infectious Diseases, St. James Hospital,, Dublin 8, Ireland. jkieran2@stjames.ie
    Issue Date
    2012-02-01T10:44:59Z
    MeSH
    Adolescent
    Adult
    Aged
    Aged, 80 and over
    Anti-Bacterial Agents/*administration & dosage/adverse effects/*therapeutic use
    Bacterial Infections/*drug therapy
    Female
    *Health Services Research
    Humans
    *Infusions, Intravenous
    Ireland
    Male
    Middle Aged
    Outpatients
    Prospective Studies
    Self Administration/*methods
    Treatment Outcome
    Young Adult
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    Citation
    Eur J Clin Microbiol Infect Dis. 2009 Nov;28(11):1369-74. Epub 2009 Aug 21.
    Journal
    European journal of clinical microbiology & infectious diseases : official, publication of the European Society of Clinical Microbiology
    URI
    http://hdl.handle.net/10147/207797
    DOI
    10.1007/s10096-009-0794-5
    PubMed ID
    19697069
    Abstract
    Outpatient parenteral antibiotic therapy (OPAT) was first reported in 1972. OPAT programmes are not well established in Ireland, with no reported outcomes in the literature. An OPAT programme was established at St. James Hospital in 2006. Demographics, diagnoses and outcomes of the first 60 courses are reported. A retrospective analysis of prospectively recorded data was performed on patients treated from March 2006 to February 2009. The data was analysed using SPSS v.17. Sixty OPAT courses were administered to 56 patients, 57 percent of which were male. The median age was 50 years, the median inpatient stay was 19 days, the median duration of OPAT was 16 days and 1,289 inpatient bed days were saved. The additional cost per day of OPAT was 167.60 euros. Vancomycin was the most prescribed antimicrobial, administered to 35%. Musculoskeletal infection was the indication for treatment in 50%. Confirmatory microbiological diagnosis was identified in 72%, most frequently due to Staphylococcus aureus (68%). Only minor adverse events were recorded. Clinical cure was achieved in 92.8%. A patient satisfaction survey showed high satisfaction. OPAT is a safe and effective way of providing parenteral antibiotic therapy in the Irish healthcare system. Better integration of funding and the appointment of Infectious Diseases specialists will facilitate its expansion.
    Language
    eng
    ISSN
    1435-4373 (Electronic)
    0934-9723 (Linking)
    ae974a485f413a2113503eed53cd6c53
    10.1007/s10096-009-0794-5
    Scopus Count
    Collections
    St. James's Hospital

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