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    Duplex ultrasound in aneurysm surveillance following endovascular aneurysm repair: a comparison with computed tomography aortography.

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    Authors
    Manning, Brian J
    O'Neill, Sean M
    Haider, Syed N
    Colgan, Mary P
    Madhavan, Prakash
    Moore, Dermot J
    Affiliation
    Department of Vascular and Endovascular Surgery, St James Hospital, Dublin,, Ireland. brianjmanning@gmail.com
    Issue Date
    2012-02-01T10:44:51Z
    MeSH
    Aged
    Aged, 80 and over
    Angiography, Digital Subtraction
    Aortic Aneurysm/*radiography/surgery/*ultrasonography
    Aortography/*methods
    *Blood Vessel Prosthesis
    Blood Vessel Prosthesis Implantation/adverse effects/*instrumentation
    Databases as Topic
    Female
    Humans
    Male
    Middle Aged
    Predictive Value of Tests
    Prospective Studies
    Prosthesis Failure
    Radiation Dosage
    Reoperation
    Sensitivity and Specificity
    *Tomography, X-Ray Computed
    Treatment Outcome
    *Ultrasonography, Doppler, Color
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    Citation
    J Vasc Surg. 2009 Jan;49(1):60-5. Epub 2008 Oct 1.
    Journal
    Journal of vascular surgery : official publication, the Society for Vascular, Surgery [and] International Society for Cardiovascular Surgery, North American, Chapter
    URI
    http://hdl.handle.net/10147/207792
    DOI
    10.1016/j.jvs.2008.07.079
    PubMed ID
    18829237
    Abstract
    OBJECTIVES: Cumulative radiation dose, cost, and increased demand for computed tomography aortography (CTA) suggest that duplex ultrasonography (DU) may be an alternative to CTA-based surveillance. We compared CTA with DU during endovascular aneurysm repair (EVAR) follow-up. METHODS: Patients undergoing EVAR had clinical and radiological follow-up data entered in a prospectively maintained database. For the purpose of this study, the gold standard test for endoleak detection was CTA, and an endoleak detected on DU alone was assumed to be a false positive result. DU interpretation was performed independently of CTA and vice versa. RESULTS: One hundred thirty-two patients underwent EVAR, of whom 117 attended for follow-up ranging from six months to nine years (mean, 32 months). Adequate aneurysm sac visualisation on DU was not possible in 1.7% of patients, predominantly due to obesity. Twenty-eight endoleaks were detected in 28 patients during follow-up. Of these, 24 were initially identified on DU (four false negative DU examinations), and eight had at least one negative CTA with a positive DU prior to diagnosis. Twenty-three endoleaks were type II in nature and three of these patients had increased sac size. There was one type I and four type III endoleaks. Two of these (both type III) had an increased sac size. Of 12 patients with increased aneurysm size of 5 mm or more at follow-up, five had an endoleak visible on DU, yet negative CTA and a further five had endoleak visualisation on both DU and CTA. Of six endoleaks which underwent re-intervention, all were initially picked up on DU. One of these endoleaks was never demonstrated on CTA and a further two had at least one negative CTA prior to endoleak confirmation. Positive predictive value for DU was 45% and negative predictive value 94%. Specificity of DU for endoleak detection was 67% when compared with CTA, because of the large number of false positive DU results. Sensitivity for DU was 86%, with all clinically significant endoleaks demonstrated on CTA also detected on DU. CONCLUSION: Despite its low positive predictive value, we found DU to be a sensitive test for the detection of clinically significant endoleaks. Given concerns about cumulative radiation exposure and cost, and the surprisingly low sensitivity of CTA for endoleak detection in this series, selective CTA based on DU surveillance may be a more appropriate long-term strategy.
    Language
    eng
    ISSN
    1097-6809 (Electronic)
    0741-5214 (Linking)
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.jvs.2008.07.079
    Scopus Count
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