Ligands, cell-based models, and readouts required for Toll-like receptor action.
Authors
Dellacasagrande, JeromeAffiliation
OPSONA Therapeutics Ltd., Trinity Centre for Health Sciences, St. James', Hospital, Dublin 8, Ireland. jdellacasgrande@opsona.comIssue Date
2012-02-01T10:44:44ZMeSH
AnimalsCell Line
Gene Expression Regulation/*genetics
Genes, Reporter/genetics
Humans
Ligands
*Models, Biological
Phosphorylation
Protein Transport
Toll-Like Receptors/*analysis/classification/genetics/*metabolism
Transcription, Genetic/genetics
Metadata
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Methods Mol Biol. 2009;517:15-32.Journal
Methods in molecular biology (Clifton, N.J.)DOI
10.1007/978-1-59745-541-1_2PubMed ID
19378025Abstract
This chapter details the tools that are available to study Toll-like receptor (TLR) biology in vitro. This includes ligands, host cells, and readouts. The use of modified TLRs to circumvent some technical problems is also discussed.Language
engISSN
1064-3745 (Print)1064-3745 (Linking)
ae974a485f413a2113503eed53cd6c53
10.1007/978-1-59745-541-1_2
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