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    Ligands, cell-based models, and readouts required for Toll-like receptor action.

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    Authors
    Dellacasagrande, Jerome
    Affiliation
    OPSONA Therapeutics Ltd., Trinity Centre for Health Sciences, St. James', Hospital, Dublin 8, Ireland. jdellacasgrande@opsona.com
    Issue Date
    2012-02-01T10:44:44Z
    MeSH
    Animals
    Cell Line
    Gene Expression Regulation/*genetics
    Genes, Reporter/genetics
    Humans
    Ligands
    *Models, Biological
    Phosphorylation
    Protein Transport
    Toll-Like Receptors/*analysis/classification/genetics/*metabolism
    Transcription, Genetic/genetics
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    Citation
    Methods Mol Biol. 2009;517:15-32.
    Journal
    Methods in molecular biology (Clifton, N.J.)
    URI
    http://hdl.handle.net/10147/207788
    DOI
    10.1007/978-1-59745-541-1_2
    PubMed ID
    19378025
    Abstract
    This chapter details the tools that are available to study Toll-like receptor (TLR) biology in vitro. This includes ligands, host cells, and readouts. The use of modified TLRs to circumvent some technical problems is also discussed.
    Language
    eng
    ISSN
    1064-3745 (Print)
    1064-3745 (Linking)
    ae974a485f413a2113503eed53cd6c53
    10.1007/978-1-59745-541-1_2
    Scopus Count
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    St. James's Hospital

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